BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/26/2020 5:49:13 AM | Browse: 857 | Download: 1639
 |
Received |
|
2020-02-28 08:53 |
|
Peer-Review Started |
|
2020-02-28 08:59 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2020-04-02 20:44 |
|
Revised |
|
2020-04-10 09:18 |
|
Second Decision |
|
2020-07-21 09:09 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2020-07-26 21:13 |
|
Articles in Press |
|
2020-07-26 21:13 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2020-08-03 02:37 |
|
Typeset the Manuscript |
|
2020-08-13 12:49 |
|
Publish the Manuscript Online |
|
2020-08-26 05:49 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Review |
| Article Title |
Stem cell therapy for Alzheimer's disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Xin-Yu Liu, Lin-Po Yang and Lan Zhao |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81202740 |
| Tianjin Natural Science Fund |
17JCYBJC26200 |
|
| Corresponding Author |
Lan Zhao, PhD, Research Fellow, Tianjin Institution of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, No. 88 Chang Ling Road, Xi Qing District, Tianjin 300381, China. lanzhao69@163.com |
| Key Words |
Alzheimer's disease; Stem cell; Therapy; Pathogenesis; Animal experiment; Clinical trial |
| Core Tip |
Alzheimer’s disease (AD), a progressive neurodegenerative disorder featuring memory loss and cognitive impairment, is caused by synaptic failure and the excessive accumulation of misfolded proteins. Stem cell-based therapies cast a new hope for AD treatment as a replacement or regeneration strategy. The results from recent preclinical studies regarding stem cell-based therapies are promising. Human clinical trials are now underway. However, a number of questions remain to be answered prior to safe and effective clinical translation. This review explores the pathophysiology of AD and summarizes the relevant stem cell research according to cell type. We also briefly summarize related clinical trials. Finally, future perspectives are discussed with regard to their clinical applications. |
| Publish Date |
2020-08-26 05:49 |
| Citation |
Liu XY, Yang LP, Zhao L. Stem cell therapy for Alzheimer's disease. World J Stem Cells 2020; 12(8): 787-802 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i8/787.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i8.787 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
