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Articles Published Processes
9/22/2020 6:23:06 AM | Browse: 798 | Download: 1817
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Received |
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2020-03-20 09:14 |
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Peer-Review Started |
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2020-03-20 09:23 |
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To Make the First Decision |
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Return for Revision |
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2020-04-29 21:55 |
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Revised |
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2020-06-20 02:59 |
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Second Decision |
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2020-07-17 09:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-07-19 21:38 |
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Articles in Press |
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2020-07-19 21:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-07-23 23:38 |
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Typeset the Manuscript |
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2020-09-18 17:10 |
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Publish the Manuscript Online |
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2020-09-22 06:23 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Human mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yunejin Song, Jung-Yeon Lim, Taekyu Lim, Keon-Il Im, Nayoun Kim, Young-Sun Nam, Young-Woo Jeon, Jong Chul Shin, Hyun Sun Ko, In Yang Park and Seok-Goo Cho |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Korean Health Technology Rnd Project |
HI16C2178 |
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| Corresponding Author |
Seok-Goo Cho, MD, PhD, Professor, Division of Hematology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Banpodaero 222, Seocho-Gu, Seoul 06591, South Korea. chosg@catholic.ac.kr |
| Key Words |
Mesenchymal stem cells; Graft-versus-host disease; Umbilical cord; Cell therapy; Xenogeneic mouse model; Immunomodulation |
| Core Tip |
Mesenchymal stem cells (MSCs) have been considered as a therapeutic approach to treat graft-versus-host disease because of their unique immunomodulatory abilities. Here, we compared and analyzed the differences and similarities between umbilical cord-derived MSCs (UC-MSCs) and bone marrow-derived MSCs (BM-MSCs) due to the growing needs for new sources of MSCs. We suggest that UC-MSCs and BM-MSCs exhibit similar immunosuppression in different mechanisms, and UC-MSCs have potentials to substitute BM-MSCs as cell therapy products. |
| Publish Date |
2020-09-22 06:23 |
| Citation |
Song Y, Lim JY, Lim T, Im KI, Kim N, Nam YS, Jeon YW, Shin JC, Ko HS, Park IY, Cho SG. Human mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms. World J Stem Cells 2020; 12(9): 1032-1049 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i9/1032.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i9.1032 |
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