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Articles Published Processes
9/22/2020 6:23:06 AM | Browse: 708 | Download: 1374
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Received |
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2020-03-03 17:02 |
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Peer-Review Started |
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2020-03-03 17:04 |
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To Make the First Decision |
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Return for Revision |
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2020-06-07 22:15 |
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Revised |
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2020-06-18 05:53 |
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Second Decision |
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2020-07-16 10:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-07-19 21:44 |
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Articles in Press |
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2020-07-19 21:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-07-29 06:03 |
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Typeset the Manuscript |
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2020-09-08 05:11 |
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Publish the Manuscript Online |
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2020-09-22 06:23 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Review |
Article Title |
Role of the CXCR4-SDF1-HMGB1 pathway in the directional migration of cells and regeneration of affected organs
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Manuscript Source |
Invited Manuscript |
All Author List |
Nazmul Haque, Ismail M Fareez, Liew Fong Fong, Chanchal Mandal, Noor Hayaty Abu Kasim, Kranthi Raja Kacharaju and Pratiwi Soesilawati |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
MAHSA University Grant |
RP158-05/19 |
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Corresponding Author |
Nazmul Haque, PhD, Senior Lecturer, Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, MAHSA University, Jalan SP 2, Bandar Saujana Putra, Selangor 42610, Malaysia. tanna.bge@gmail.com |
Key Words |
C-X-C motif chemokine 12; Mesenchymal stem cells; Monocytes; Neutrophils; Peripheral blood mononuclear cells; Receptor for advanced glycation end products |
Core Tip |
In the last few decades cell based regenerative therapy received considerable attention to treat the degenerative diseases or to regenerate injured organs. However, poor cell retention is considered a major drawback behind its short-term regenerative benefits. Furthermore, the short-term regenerative benefits were linked to the paracrine factors secreted by the transplanted stem cells. In search for the solution to improve regenerative outcomes, researchers identified the role of stromal cell-derived factor-1 (SDF1) as a key chemotactic factor that could facilitate site specific migration and retention of the transplanted cells, and the stem or progenitor cells within the body by activating SDF1-CXCR4 or HMGB1-SFD1-CXCR4 pathways. |
Publish Date |
2020-09-22 06:23 |
Citation |
Haque N, Fareez IM, Fong LF, Mandal C, Abu Kasim NH, Kacharaju KR, Soesilawati P. Role of the CXCR4-SDF1-HMGB1 pathway in the directional migration of cells and regeneration of affected organs. World J Stem Cells 2020; 12(9): 938-951 |
URL |
https://www.wjgnet.com/1948-0210/full/v12/i9/938.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v12.i9.938 |
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