Publication Name	World Journal of Clinical Oncology
Manuscript ID	55354
Country	Germany

Received	2020-03-12 11:12
Peer-Review Started	2020-03-12 11:13
To Make the First Decision
Return for Revision	2020-06-07 22:13
Revised	2020-06-11 12:00
Second Decision	2020-07-16 11:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-07-19 21:57
Articles in Press	2020-07-19 21:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-08-17 06:52
Publish the Manuscript Online	2020-08-21 01:38

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Proton beam therapy of periorbital sinonasal squamous cell carcinoma: Two case reports and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Lan Lin
ORCID	Author(s) ORCID Number Yi-Lan Lin http://orcid.org/0000-0001-6283-9205
Funding Agency and Grant Number
Corresponding Author	Yi-Lan Lin, MD, Chief Doctor, Chief Physician, Department of Radiation Oncology, Rinecker Proton Therapy Center, Schaeftlarnstr. 133, Munich 81371, Germany. liny0630@googlemail.com; yi-lan.lin@web.de
Key Words	Proton beam therapy; Intensity modulated proton therapy; Sinonasal malignancies; Squamous cell carcinoma; Orbital exenteration; Case report
Core Tip	The treatment of sinonasal squamous cell carcinoma is exceedingly challenging owing to complex anatomy, delayed diagnosis, and lack of randomized clinical studies about multimodality approaches. In particular, locally advanced disease with indication of orbital exenteration or other disfiguring surgeries, as well as unresectable gross tumor require modern non-surgical treatment options like proton beam therapy, as presented in this case report, to achieve a long-term tumor control without severe late toxicities, such as blindness and cerebral radiation necrosis.
Publish Date	2020-08-21 01:38
Citation	Lin YL. Proton beam therapy of periorbital sinonasal squamous cell carcinoma: Two case reports and review of literature. World J Clin Oncol 2020; 11(8): 655-672
URL	https://www.wjgnet.com/2218-4333/full/v11/i8/655.htm
DOI	https://dx.doi.org/10.5306/wjco.v11.i8.655

Full Article (PDF)	WJCO-11-655.pdf
Full Article (Word)	WJCO-11-655.docx
CARE Checklist–2016	55354-CARE-Checklist–2016-revision.pdf
Manuscript File	55354-Review.docx
Answering Reviewers	55354-Answering reviewers.pdf
Audio Core Tip	55354-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	55354-Conflict-of-interest statement.pdf
Copyright License Agreement	55354-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	55354-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	55354-Language certificate.pdf
Peer-review Report	55354-Peer-review(s).pdf
Scientific Misconduct Check	55354-Bing-Yan JP-1.png
Scientific Misconduct Check	55354-Bing-Yan JP-2.png
Scientific Misconduct Check	55354-Scientific misconduct check.pdf
Scientific Editor Work List	55354-Scientific editor work list.pdf
CrossCheck Report	55354-CrossCheck Report.pdf