| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Feng Xing, Chun-Shan Wei, Tian-Ran Zhou, Dan-Ping Huang, Wei-Chao Zhong, Bin Chen, Hua Jin, Xiao-Yu Hu, Zhi-Yun Yang, Qing He, Kai-Ping Jiang, Jun-Min Jiang, Zhen-Bin Hu, Xin Deng, Fan Yang, Feng-Yi Li, Gang Zhao, Li-Chun Wang, Yu-Qiang Mi, Zuo-Jiong Gong, Peng Guo, Jian-Hua Wu, Wei-Qun Shi, Hong-Zhi Yang, Da-Qiao Zhou and Guang-Dong Tong |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81174263 |
| National Science and Technology Major Project during the 12th Five-year Plan Period |
2012ZX1005006 |
| Sanming Project of Medicine in Shenzhen, Guangdong Province, China |
SZSM201612074 |
| Science and Technology Planning Project of Guangdong Province, China |
2017A020213016 |
|
| Corresponding Author |
Guang-Dong Tong, MD, Professor, Department of Hepatology, Shenzhen Traditional Chinese Medicine Hospital, No. 1 Fuhua Road, Futian District, Shenzhen 518033, China. tgd755@163.com |
| Key Words |
Chronic hepatitis B; Chinese Herbal Formula treatment; Hepatitis B e antigen clearance; Hepatitis B e antigen seroconversion; Hepatitis B virus DNA reduction; Clinical trial |
| Core Tip |
Hepatitis B e antigen-positive chronic hepatitis B patients with persistently normal alanine aminotransferase levels and a high hepatitis B virus (HBV) DNA viral load may progress to cirrhosis or hepatocellular carcinoma. However, no guideline recommends antiviral therapy for it because of poor efficacy. In the present study we report the feasibility and safety profiles of a Chinese herbal formula as a therapeutic option for chronic HBV infection. |
| Publish Date |
2020-08-14 12:33 |
| Citation |
Xing YF, Wei CS, Zhou TR, Huang DP, Zhong WC, Chen B, Jin H, Hu XY, Yang ZY, He Q, Jiang KP, Jiang JM, Hu ZB, Deng X, Yang F, Li FY, Zhao G, Wang LC, Mi YQ, Gong ZJ, Guo P, Wu JH, Shi WQ, Yang HZ, Zhou DQ, Tong GD. Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients. World J Gastroenterol 2020; 26(30): 4501-4522 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i30/4501.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i30.4501 |
