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Articles Published Processes
9/11/2014 8:40:00 PM | Browse: 1315 | Download: 1080
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Received |
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2013-09-14 09:11 |
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Peer-Review Started |
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2013-09-14 19:47 |
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To Make the First Decision |
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2013-09-27 16:29 |
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Return for Revision |
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2013-09-30 11:03 |
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Revised |
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2013-10-16 15:58 |
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Second Decision |
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2013-11-04 18:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-11-05 10:37 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-11-14 22:02 |
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Typeset the Manuscript |
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2013-11-26 19:45 |
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Publish the Manuscript Online |
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2013-12-18 10:39 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Helicobacter pylori and interleukin-8 in gastric cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Ko Eun Lee, Pham Ngoc Khoi, Yong Xia, Jung Sun Park, Young Eun Joo, Kyung Keun Kim, Seok Yong Choi and Young Do Jung |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
A research grant from the National Cancer Center |
0720570 |
National Research Foundation of Korea (NRF) |
2010-0009910 |
Korea government (MSIP) |
2011-0030132 |
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Corresponding Author |
Young Do Jung, MD, PhD, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-190, South Korea. ydjung@chonnam.ac.kr |
Key Words |
Helicobacter pylori; Interleukin-8; Signals; Gastric cancer; Therapeutics |
Core Tip |
There is a close association between gastric cancer and Helicobacter pylori (H. pylori) infection. H. pylori upregulates interleukin-8 (IL-8) gene expression in gastric epithelial cells and the levels of IL-8 may be indicative of poor prognosis. We propose that IL-8 overexpression induced by H. pylori plays a major role in gastric cancer development and progression, and that targeting IL-8 may be a promising strategy for gastric cancer treatment. |
Publish Date |
2013-12-18 10:39 |
Citation |
Lee KE, Khoi PN, Xia Y, Park JS, Joo YE, Kim KK, Choi SY, Jung YD. Helicobacter pylori and interleukin-8 in gastric cancer. World J Gastroenterol 2013; 19(45): 8192-8202 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i45/8192.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i45.8192 |
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