Publication Name	World Journal of Gastroenterology
Manuscript ID	5548
Country	South Korea

Received	2013-09-14 09:11
Peer-Review Started	2013-09-14 19:47
First Decision by Editorial Office Director
Return for Revision	2013-09-30 11:03
Revised	2013-10-16 15:58
Publication Fee Transferred
Second Decision by Editor	2013-11-04 18:07
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-11-05 10:37
Articles in Press
Edit the Manuscript by Language Editor	2013-11-14 22:02
Typeset the Manuscript	2013-11-26 19:45
Publish the Manuscript Online	2013-12-18 10:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Helicobacter pylori and interleukin-8 in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Ko Eun Lee, Pham Ngoc Khoi, Yong Xia, Jung Sun Park, Young Eun Joo, Kyung Keun Kim, Seok Yong Choi and Young Do Jung
Funding Agency and Grant Number	Funding Agency Grant Number A research grant from the National Cancer Center 0720570 National Research Foundation of Korea (NRF) 2010-0009910 Korea government (MSIP) 2011-0030132
Corresponding Author	Young Do Jung, MD, PhD, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-190, South Korea. ydjung@chonnam.ac.kr
Key Words	Helicobacter pylori; Interleukin-8; Signals; Gastric cancer; Therapeutics
Core Tip	There is a close association between gastric cancer and Helicobacter pylori (H. pylori) infection. H. pylori upregulates interleukin-8 (IL-8) gene expression in gastric epithelial cells and the levels of IL-8 may be indicative of poor prognosis. We propose that IL-8 overexpression induced by H. pylori plays a major role in gastric cancer development and progression, and that targeting IL-8 may be a promising strategy for gastric cancer treatment.
Publish Date	2013-12-18 10:39
Citation	Lee KE, Khoi PN, Xia Y, Park JS, Joo YE, Kim KK, Choi SY, Jung YD. Helicobacter pylori and interleukin-8 in gastric cancer. World J Gastroenterol 2013; 19(45): 8192-8202
URL	http://www.wjgnet.com/1007-9327/full/v19/i45/8192.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i45.8192

Full Article (PDF)	WJG-19-8192.pdf
Manuscript File	5548-Review.doc
Answering Reviewers	5548-Answering reviewers.pdf
Copyright License Agreement	5548-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20130913160550.pdf
Peer-review Report	5548-Peer reviewer(s).pdf
Scientific Editor Work List	5548-Scientific editor work list.doc