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Articles Published Processes
8/25/2020 9:16:00 AM | Browse: 464 | Download: 834
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Received |
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2020-03-31 15:53 |
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Peer-Review Started |
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2020-03-31 15:58 |
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To Make the First Decision |
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Return for Revision |
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2020-07-05 14:53 |
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Revised |
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2020-07-08 03:00 |
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Second Decision |
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2020-07-21 09:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-07-26 21:28 |
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Articles in Press |
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2020-07-26 21:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-08-05 11:27 |
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Publish the Manuscript Online |
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2020-08-25 09:16 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Non-islet cell tumor hypoglycemia as an initial presentation of hepatocellular carcinoma coupled with end-stage liver cirrhosis: A case report and literature review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bo Yu, Rana Douli, Jose Amaya Suarez, Victor Perez Gutierrez, Mohammad Aldiabat and Maria Khan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bo Yu, MD, MSc, Doctor, Department of Medicine, Lincoln Medical Center, 234 E.149th Street, Bronx, NY 10451-5504, United States. yub3@nychhc.org |
| Key Words |
Non-islet cell tumor hypoglycemia; Hepatocellular carcinoma; Liver cirrhosis; Insulin-like growth factor-2; Paraneoplastic syndrome; Case report |
| Core Tip |
Paraneoplastic Non-islet cell tumor hypoglycemia can occur as an initial presentation in patients with hepatocellular carcinoma and is often difficult to correct. It is tend to be underdiagnosed because patients often developed tolerance to chronic fasting hypoglycemia secondary to advanced liver cirrhosis. A ratio of insulin-like growth factor-2/insulin-like growth factor-1 above 10 is often found if non-islet cell tumor hypoglycemia is induced by overproduction of incompletely processed insulin-like growth factor-2. Oral corticosteroids and frequent high carbohydrate meals are often recommended but the outcome is unfavorable in general if tumor removal is not possible. |
| Publish Date |
2020-08-25 09:16 |
| Citation |
Yu B, Douli R, Suarez JA, Gutierrez VP, Aldiabat M, Khan M. Non-islet cell tumor hypoglycemia as an initial presentation of hepatocellular carcinoma coupled with end-stage liver cirrhosis: A case report and review of literature. World J Hepatol 2020; 12(8): 519-524 |
| URL |
https://www.wjgnet.com/1948-5182/full/v12/i8/519.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v12.i8.519 |
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