Publication Name	World Journal of Gastroenterology
Manuscript ID	5601
Country	Germany

Received	2013-09-17 14:48
Peer-Review Started	2013-09-17 19:07
To Make the First Decision	2013-12-26 11:34
Return for Revision	2013-12-30 08:47
Revised	2014-01-03 19:48
Second Decision	2014-04-29 12:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-29 14:16
Articles in Press	2014-05-23 11:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-13 17:00
Typeset the Manuscript	2014-08-20 11:36
Publish the Manuscript Online	2014-09-07 13:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Chronic hepatitis B in 2014: Great therapeutic progress, large diagnostic deficit
Manuscript Source	Invited Manuscript
All Author List	Claus Niederau
Funding Agency and Grant Number
Corresponding Author	Claus Niederau, Professor, Katholisches Klinikum Oberhausen GmbH, St. Josef Hospital, Klinik für Innere Medizin, Akademisches Lehrkrankenhaus der Universität Duisburg-Essen, Mülheimer Str. 83, 46045 Oberhausen, Germany. c.niederau@kk-ob.de
Key Words	Chronic hepatitis B; HBsAg; Screening; Liver cirrhosis; Hepatocellular cancer; Entecavir; Tenofovi; Telbivudine; Adefovir; Lamivudine; Interferon
Core Tip	This review analyzes progress and limitations of diagnosis, screening, and therapy of patients with chronic hepatitis B. Treatment can control viral replication in most patients today. It reduces risks for progression and may reverse fibrosis. However, screening recommendations have not been implemented, and the performance of hepatocellular carcinoma surveillance is poor. Many patients with chronic hepatitis B live in resource-constrained settings where effective drugs are not available. Despite the therapeutic progress, chronic hepatitis B remains a problem since many patients do not know of their disease. These problems may be overcome by raising awareness, promoting partnerships, and mobilizing resources.
Publish Date	2014-09-07 13:31
Citation	Niederau C. Chronic hepatitis B in 2014: Great therapeutic progress, large diagnostic deficit. World J Gastroenterol 2014; 20(33): 11595-11617
URL	http://www.wjgnet.com/1007-9327/full/v20/i33/11595.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i33.11595

Full Article (PDF)	WJG-20-11595.pdf
Full Article (Word)	WJG-20-11595.doc
Manuscript File	5601-Review.docx
Answering Reviewers	5601-Answering reviewers.pdf
Copyright License Agreement	5601-Copyright assignment.pdf
Peer-review Report	5601-Peer review.pdf
Scientific Editor Work List	5601-Scientific editor work list.pdf