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Articles Published Processes
11/24/2020 12:41:22 PM | Browse: 477 | Download: 1333
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Received |
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2020-04-13 14:25 |
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Peer-Review Started |
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2020-04-13 14:26 |
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To Make the First Decision |
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Return for Revision |
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2020-06-24 21:35 |
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Revised |
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2020-08-11 22:07 |
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Second Decision |
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2020-09-02 12:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-09-03 02:40 |
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Articles in Press |
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2020-09-03 02:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-09-24 01:52 |
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Publish the Manuscript Online |
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2020-11-24 12:41 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Occurrence of seeding metastases in resectable perihilar cholangiocarcinoma and the role of low-dose radiotherapy to prevent this
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lotte C Franken, Eva Roos, Job Saris, Jeanin E van Hooft, Otto M van Delden, Joanne Verheij, Joris I Erdmann, Marc G Besselink, Olivier R Busch, Geertjan van Tienhoven and Thomas M van Gulik |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lotte C Franken, MD, Research Fellow, Department of Surgery，Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, Netherlands. l.c.franken@amc.uva.nl |
| Key Words |
Perihilar cholangiocarcinoma; Seeding metastases; Preventive radiotherapy; ; ; |
| Core Tip |
Routine preoperative radiotherapy (3 times 3.5 Gray) to prevent the occurrence of seeding metastases was used in our tertiary center for 28 years in patients undergoing resection for perihilar cholangiocarcinoma. Seeding metastases occurred in 2 out of 171 patients (1.2%) undergoing resection between 2000 and 2019. Intraoperative bile cytology showed no significant difference in the presence of tumor cells in the bile of patients undergoing preoperative radiotherapy or not. Due to the current low incidence of seeding metastases, preoperative radiotherapy to prevent seeding metastases is now abandoned in our institution. |
| Publish Date |
2020-11-24 12:41 |
| Citation |
Franken LC, Roos E, Saris J, van Hooft J, van Delden O, Verheij J, Erdmann J, Besselink MG, Busch OR, van Tienhoven G, van Gulik TM. Occurrence of seeding metastases in resectable perihilar cholangiocarcinoma and the role of low-dose radiotherapy to prevent this. World J Hepatol 2020; 12(11): 1089-1097 |
| URL |
https://www.wjgnet.com/1948-5182/full/v12/i11/1089.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v12.i11.1089 |
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