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8/14/2020 12:33:31 PM | Browse: 1286 | Download: 3406
Publication Name World Journal of Gastroenterology
Manuscript ID 56043
Country China
Received
2020-04-22 07:13
Peer-Review Started
2020-04-22 07:14
First Decision by Editorial Office Director
2020-06-13 02:54
Return for Revision
2020-06-13 02:54
Revised
2020-06-24 23:31
Publication Fee Transferred
Second Decision by Editor
2020-07-15 13:07
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2020-07-16 01:51
Articles in Press
2020-07-16 01:51
Edit the Manuscript by Language Editor
2020-07-28 02:17
Typeset the Manuscript
2020-08-14 00:49
Publish the Manuscript Online
2020-08-14 12:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title High levels of serum interleukin-6 increase mortality of hepatitis B virus-associated acute-on-chronic liver failure
Manuscript Source Unsolicited Manuscript
All Author List Chao Zhou, Ning Zhang, Ting-Ting He, Yao Wang, Li-Fu Wang, Yong-Qiang Sun, Jing Jing, Jing-Jing Zhang, Shuang-Nan Fu, Xuan Wang, Xiao-Xiao Liang, Xin Li, Man Gong and Jun Li
ORCID
Author(s) ORCID Number
Chao Zhou http://orcid.org/0000-0002-2665-2889
Ning Zhang http://orcid.org/0000-0002-6826-9175
Ting-Ting He http://orcid.org/0000-0003-1947-5308
Yao Wang http://orcid.org/0000-0002-4651-3077
Li-Fu Wang http://orcid.org/0000-0002-1419-4809
Yong-Qiang Sun http://orcid.org/0000-0001-6340-158X
Jing Jing http://orcid.org/0000-0002-6290-6268
Jing-Jing Zhang http://orcid.org/0000-0002-0207-9053
Shuang-Nan Fu http://orcid.org/0000-0001-8278-4555
Xuan Wang http://orcid.org/0000-0003-2526-008X
Xiao-Xiao Liang http://orcid.org/0000-0002-4067-6473
Xin Li http://orcid.org/0000-0002-4930-5433
Man Gong http://orcid.org/0000-0003-2716-4331
Jun Li http://orcid.org/0000-0001-9964-1657
Funding Agency and Grant Number
Funding Agency Grant Number
National Thirteen Five-year Great Science and Technology Project 2018ZX10725506-002
National Twelve Five-year Great Science and Technology Project 2012ZX10005-005
Corresponding Author Man Gong, MD, Associate Professor, Department of Integrative Medicine, 5th Medical Center of Chinese PLA General Hospital, No. 100, the 4th Ring Road, Beijing 100039, China. gongman302@163.com
Key Words Hepatitis B virus; Liver failure; Prognosis; Interleukin 6; /; /
Core Tip To triage and prognosticate the outcome is vital for management of patients with hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF). Interleukin 6 (IL-6) is related with physiology and pathology of the liver. We found a high level of serum IL-6 was an independent risk factor for mortality in patients with HBV-ACLF. HBV-ACLF patients with high level of IL-6 showed high mortality, especially with persistent high level within 4 wk, indicating that IL-6 was an index of prognosis for HBV-ACLF.
Publish Date 2020-08-14 12:33
Citation Zhou C, Zhang N, He TT, Wang Y, Wang LF, Sun YQ, Jing J, Zhang JJ, Fu SN, Wang X, Liang XX, Li X, Gong M, Li J. High levels of serum interleukin-6 increase mortality of hepatitis B virus-associated acute-on-chronic liver failure. World J Gastroenterol 2020; 26(30): 4479-4488
URL https://www.wjgnet.com/1007-9327/full/v26/i30/4479.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i30.4479
Full Article (PDF) WJG-26-4479.pdf
Full Article (Word) WJG-26-4479.docx