Publication Name	World Journal of Gastroenterology
Manuscript ID	5618
Country	Japan

Received	2013-09-17 12:12
Peer-Review Started	2013-09-17 17:16
To Make the First Decision	2013-10-14 21:28
Return for Revision	2013-10-20 18:56
Revised	2013-11-14 19:48
Second Decision	2013-12-03 21:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-04 06:34
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-06 09:52
Publish the Manuscript Online	2014-02-19 16:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Helicobacter pylori-associated immune thrombocytopenia: Clinical features and pathogenic mechanisms
Manuscript Source	Invited Manuscript
All Author List	Masataka Kuwana
Funding Agency and Grant Number	Funding Agency Grant Number Research on Intractable Diseases from the Japanese Ministry of Health, Labor, and Welfare H23-Nanchi-Ippan-002
Corresponding Author	Masataka Kuwana, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. kuwanam@z5.keio.jp
Key Words	Autoantibody; Childhood; Helicobacter pylori; Fcγ receptor; Immune thrombocytopenia; Idiopathic thrombocytopenic purpura; Systemic lupus erythematosus
Core Tip	In this review, we summarize recent updates on basic and clinical aspects of Helicobacter pylori (H. pylori)-associated immune thrombocytopenia (ITP). We highlight the efficacy of H. pylori eradication in adult and childhood ITP as well as in secondary ITP, variability in the efficacy of eradication in various countries, factors predicting the eradication-related platelet response, and the mechanisms responsible for the development of ITP in association with H. pylori infection. It is apparent that in a distinct subgroup of H. pylori-associated ITP, this bacterial infection is central to the ITP pathogenesis.
Publish Date	2014-02-19 16:57
Citation	Kuwana M. Helicobacter pylori-associated immune thrombocytopenia: clinical features and pathogenic mechanisms. World J Gastroenterol 2014; 20(3): 714-723
URL	http://www.wjgnet.com/1007-9327/full/v20/i3/714.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i3.714

Full Article (PDF)	WJG-20-714.pdf
Full Article (Word)	WJG-20-714.doc
Manuscript File	5618-Review.doc
Answering Reviewers	5618-Answering reviewers.pdf
Copyright License Agreement	5618-Copyright assignment.pdf
Peer-review Report	5618-Peer reviewer(s).pdf
Scientific Editor Work List	5618-Scientific editor work list.doc