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Articles Published Processes
9/10/2020 5:57:28 AM | Browse: 736 | Download: 1611
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Received |
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2020-04-22 07:12 |
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Peer-Review Started |
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2020-04-22 07:14 |
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To Make the First Decision |
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Return for Revision |
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2020-04-26 17:39 |
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Revised |
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2020-07-16 07:07 |
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Second Decision |
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2020-08-14 09:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-08-16 18:13 |
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Articles in Press |
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2020-08-16 18:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-08-28 08:35 |
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Typeset the Manuscript |
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2020-09-07 02:04 |
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Publish the Manuscript Online |
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2020-09-10 05:57 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Case Report |
Article Title |
Response of human epidermal growth factor receptor 2-positive colorectal cancer to lapatinib monotherapy: A case report
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ji-Lin Guan, Jian-Hua Liu, Qing Wang, Yu-Wei Cong, Yao-Xu Chen, Ke-Fei Huang, Meng-Li Huang and Ling Huang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ling Huang, MD, Director, Director, Doctor, Doctor, Professor, Department of Oncology, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, No. 123, Hui Fuxi Road, Yuexiu District, Guangzhou 510655, Guangdong Province, China. 13710351111@139.com |
Key Words |
Human epidermal growth factor receptor 2; Colorectal cancer; Lapatinib; Circulating tumor deoxyribonucleic acid; Case report; |
Core Tip |
While dual anti- human epidermal growth factor receptor 2 (HER2) therapies are recommend as standard treatment for HER2-positive advanced colorectal cancer, anti-HER2 monotherapy is rarely used to treat this population. This case is the first report of a HER2-positive RAS/BRAF-wild-type metastatic colorectal cancer patient achieving partial response following lapatinib monotherapy without serious adverse events. Next generation sequencing based circulating tumor deoxyribonucleic acid testing played an essential role in both treatment decision and efficacy/resistance monitoring. |
Publish Date |
2020-09-10 05:57 |
Citation |
Guan JL, Liu JH, Wang Q, Cong YW, Chen YX, Huang KF, Huang ML, Huang L. Response of human epidermal growth factor receptor 2-positive colorectal cancer to lapatinib monotherapy: A case report. World J Gastrointest Oncol 2020; 12(9): 1065-1072 |
URL |
https://www.wjgnet.com/1948-5204/full/v12/i9/1065.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v12.i9.1065 |
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