Publication Name	World Journal of Gastroenterology
Manuscript ID	5626
Country	United States

Received	2013-09-18 09:38
Peer-Review Started	2013-09-18 17:55
To Make the First Decision	2013-10-29 12:45
Return for Revision	2013-11-01 17:50
Revised	2014-01-06 14:30
Second Decision	2014-04-16 11:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-16 12:23
Articles in Press	2014-05-23 10:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-17 10:32
Publish the Manuscript Online	2014-08-29 11:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Non-pulmonary allergic diseases and inflammatory bowel disease: A qualitative review
Manuscript Source	Invited Manuscript
All Author List	David S Kotlyar, Mili Shum, Jennifer Hsieh, Wojciech Blonski and David A Greenwald
Funding Agency and Grant Number	Funding Agency Grant Number NIH Intramural Program to Kotlyar DS NCI Fellowship Program, NIH
Corresponding Author	Correspondence to: David A Greenwald, MD, Professor, Division of Gastroenterology and Liver Diseases, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, 625 Ullman Building, 1300 Morris Park Avenue, Bronx, NY 10461, United States. dgreenwa@montefiore.org
Key Words	Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Food intolerance; Food allergies; Biomarkers; Pathophysiology; Nutrition; Probiotics
Core Tip	There are multiple clinical, pathophysiological and therapeutic commonalities between nonpulmonary allergic disease and inflammatory bowel disease (IBD). In particular, in terms of pathophysiology, histamine expression is upregulated in both IBD and allergic diseases. Ulcerative colitis, in particular, shows upregulation of the Th2 pathway which is seen in a large number of allergic phenomena including sinonasal disease. Both probiotics and nutritional interventions are promising therapies for both IBD and allergic disease (especially food intolerance, food allergies, and eczema) but these require more investigation. Recommending mothers breastfeed their infants, and for a longer duration also shows potential promise in prevention of both IBD and food allergies, but also requires further study.
Publish Date	2014-08-29 11:57
Citation	Kotlyar DS, Shum M, Hsieh J, Blonski W, Greenwald DA. Non-pulmonary allergic diseases and inflammatory bowel disease: A qualitative review. World J Gastroenterol 2014; 20(32): 11023-11032
URL	http://www.wjgnet.com/1007-9327/full/v20/i32/11023.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i32.11023

Full Article (PDF)	WJG-20-11023.pdf
Full Article (Word)	WJG-20-11023.doc
Manuscript File	5626-Review.docx
Answering Reviewers	5626-Answering reviewers.pdf
Copyright License Agreement	5626-Copyright assignment.pdf
Peer-review Report	5626-Peer reviewer(s).pdf
Scientific Editor Work List	5626-Scientific editor work list.doc