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Articles Published Processes
9/11/2014 8:39:00 PM | Browse: 951 | Download: 761
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Received |
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2013-09-18 11:12 |
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Peer-Review Started |
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2013-09-18 15:32 |
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To Make the First Decision |
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2013-10-14 21:27 |
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Return for Revision |
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2013-10-20 19:57 |
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Revised |
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Second Decision |
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2013-12-03 21:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-12-04 06:36 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-12-13 08:47 |
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Publish the Manuscript Online |
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2014-01-20 16:41 |
Category |
Virology |
Manuscript Type |
Topic Highlights |
Article Title |
Post-translational modifications of hepatitis C viral proteins and their biological significance
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Manuscript Source |
Invited Manuscript |
All Author List |
Jana Hundt, Zhubing Li and Qiang Liu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Canadian Institutes of Health Research |
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Saskatchewan Health Research Foundation |
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Natural Sciences and Engineering Research Council of Canada |
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Corresponding Author |
Qiang Liu, PhD, Vaccine and Infectious Disease Organization-International Vaccine Center, University of Saskatchewan, 120 Veterinary Road, Saskatoon, SK S7N 5E3, Canada. qiang.liu@usask.ca |
Key Words |
Hepatitis C virus; Hepatitis C virus proteins; Post-translational modifications of proteins; Hepatitis C virus replication; Hepatitis C virus pathogenesis |
Core Tip |
Post-translational modifications (PTMs) are an important step in protein maturation and associated with protein function, activity and/or protein life span. PTMs of viral proteins are often essential for regulation of processes involved in viral infections and can be crucial for infectious virion production. Moreover, identification of PTM sites in viral proteins is particularly useful for the development of antiviral drugs. This overview on PTMs of hepatitis C virus (HCV) proteins discusses how PTMs affect HCV replication and virus-induced pathogenesis. |
Publish Date |
2014-01-20 16:41 |
Citation |
Hundt J, Li Z, Liu Q. Post-translational modifications of hepatitis C viral proteins and their biological significance. World J Gastroenterol 2013; 19(47): 8929-8939 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i47/8929.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i47.8929 |
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