Publication Name	World Journal of Gastroenterology
Manuscript ID	5647
Country	Greece

Received	2013-09-19 09:03
Peer-Review Started	2013-09-19 17:55
To Make the First Decision	2013-10-14 21:27
Return for Revision	2013-10-20 19:58
Revised	2013-10-29 22:48
Second Decision	2014-01-06 17:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-06 19:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-04 16:25
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Individualization of chronic hepatitis C treatment according to the host characteristics
Manuscript Source	Invited Manuscript
All Author List	Nikolaos K Gatselis, Kalliopi Zachou, Asterios Saitis, Maria Samara and George N Dalekos
Funding Agency and Grant Number
Corresponding Author	George N Dalekos, MD, PhD, Professor, Head, Department of Medicine and Research Laboratory of Internal Medicine, School of Medicine, University of Thessaly, Biopolis, 41110 Larissa, Greece. dalekos@med.uth.gr
Key Words	Chronic hepatitis C; Hepatitis C virus host factors; Interleukin 28B; Inosine triphosphatase; Single nucleotide polymorphism
Core Tip	Hepatitis C virus (HCV) is a major health problem with personal, social and economic implications. In the past few years, advances in HCV molecular virology and host genetics revealed a complex interplay between the virus and the host that influence the natural history of chronic hepatitis C (CHC) and response to treatment. Besides, the management of CHC has evolved with the development of direct acting antiviral agents (DAAs). In this review, we have summarized the knowledge regarding host determinants of HCV treatment outcome and consider how this knowledge might help to individualize clinical management in the era of DAAs.
Publish Date	2014-03-18 14:14
Citation	Gatselis NK, Zachou K, Saitis A, Samara M, Dalekos GN. Individualization of chronic hepatitis C treatment according to the host characteristics. World J Gastroenterol 2014; 20(11): 2839-2853
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/2839.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.2839

Full Article (PDF)	WJG-20-2839.pdf
Full Article (Word)	WJG-20-2839.doc
Manuscript File	5647-Review.doc
Answering Reviewers	5647-Answering reviewers.pdf
Copyright License Agreement	5647-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5647-Language certificate.doc
Peer-review Report	5647-Peer reviewer(s).pdf
Scientific Editor Work List	5647-Scientific editor work list.doc