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Articles Published Processes
9/1/2014 2:51:00 PM | Browse: 851 | Download: 829
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Received |
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2013-09-20 10:04 |
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Peer-Review Started |
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2013-09-21 19:37 |
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To Make the First Decision |
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2013-10-14 21:27 |
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Return for Revision |
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2013-10-20 21:16 |
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Revised |
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2013-11-11 08:25 |
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Second Decision |
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2014-01-06 17:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-06 19:05 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-02-28 15:10 |
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Publish the Manuscript Online |
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2014-03-18 14:14 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Chronic hepatitis C genotype 1 virus: Who should wait for treatment?
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Manuscript Source |
Invited Manuscript |
All Author List |
Cristiane Valle Tovo, Angelo Alves de Mattos and Paulo Roberto Lerias de Almeida |
Funding Agency and Grant Number |
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Corresponding Author |
Cristiane Valle Tovo, MD, PhD, Department of Gastroenterology, Universidade Federal de Ciências da Saúde de Porto Alegre, Rua Cel Aurélio Bitencourt 115 apto 201, Porto Alegre 90430-080, Brazil. cris.tovo@terra.com.br |
Key Words |
Hepatitis C virus; Chronic hepatitis C; Treatment of hepatitis C; Cirrhosis; Protease inhibitors |
Core Tip |
Identification of risk factors for progression of chronic hepatitis C has allowed physicians to recommend treatment deferral (triple therapy) to wait for anticipated new drugs with better efficacy and safety profiles for patients with mild to moderate disease. Patients with cirrhosis and prior null responders rarely obtain sustained virological response with triple therapy and the decision to wait for new treatments must be considered. For each patient population, definitive clinical management guidelines are needed to maximize the benefit of waiting for new drugs and minimize risk of side effects and non-response to the current triple therapy. |
Publish Date |
2014-03-18 14:14 |
Citation |
Tovo CV, Alves de Mattos A, Lerias de Almeida PR. Chronic hepatitis C genotpype 1 virus: Who should wait for treatment? World J Gastroenterol 2014; 20(11): 2867-2875 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i11/2867.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i11.2867 |
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