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Articles Published Processes
10/28/2020 8:26:09 AM | Browse: 771 | Download: 2022
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Received |
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2020-05-12 08:33 |
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Peer-Review Started |
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2020-05-12 08:33 |
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To Make the First Decision |
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Return for Revision |
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2020-06-18 06:02 |
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Revised |
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2020-06-25 02:16 |
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Second Decision |
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2020-09-17 12:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-09-17 18:05 |
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Articles in Press |
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2020-09-17 18:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-09-22 21:06 |
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Typeset the Manuscript |
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2020-10-26 13:15 |
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Publish the Manuscript Online |
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2020-10-28 08:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Case Report |
| Article Title |
Compromised therapeutic value of pediatric liver transplantation in ethylmalonic encephalopathy: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guang-Peng Zhou, Wei Qu, Zhi-Jun Zhu, Li-Ying Sun, Lin Wei, Zhi-Gui Zeng and Ying Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beijing Municipal Science & Technology Commission |
Z181100001718220 |
| Capital's Funds for Health Improvement and Research |
2020-1-2024 |
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| Corresponding Author |
Zhi-Jun Zhu, MD, PhD, Chief Doctor, Doctor, Doctor, Professor, Surgeon, Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong-an Road, Xi-Cheng District, Beijing 100050, China. zhu-zhijun@outlook.com |
| Key Words |
Ethylmalonic encephalopathy; Liver transplantation; Mitochondrial disorder; ETHE1; Pediatric; Case report |
| Core Tip |
Liver transplantation (LT) is emerging as a novel therapeutic option for ethylmalonic encephalopathy (EE). However, worldwide experience is still limited. Our case of LT for EE, to the best of our knowledge, is the first case in Asian-Pacific countries. The case suggests that despite only a partial cure, LT does have a definite role in defending against the devastating natural progression of EE. Early establishment of diagnosis and initiation of conventional treatment pre-transplant, timely LT, and continuous administration of metabolism-correcting medications post-transplant may be helpful in minimizing the neurologic impairment and maximizing the therapeutic value of LT in EE. |
| Publish Date |
2020-10-28 08:26 |
| Citation |
Zhou GP, Qu W, Zhu ZJ, Sun LY, Wei L, Zeng ZG, Liu Y. Compromised therapeutic value of pediatric liver transplantation in ethylmalonic encephalopathy: A case report. World J Gastroenterol 2020; 26(40): 6295-6303 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i40/6295.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i40.6295 |
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