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Articles Published Processes
11/6/2020 8:18:52 AM | Browse: 820 | Download: 1815
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Received |
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2020-05-07 20:08 |
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Peer-Review Started |
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2020-05-06 22:01 |
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To Make the First Decision |
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Return for Revision |
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2020-06-07 22:05 |
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Revised |
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2020-06-18 19:13 |
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Second Decision |
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2020-10-09 09:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-09 16:43 |
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Articles in Press |
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2020-10-09 16:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-11-02 01:02 |
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Publish the Manuscript Online |
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2020-11-06 08:18 |
ISSN |
2150-5349 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Oral encapsulated transforming growth factor β1 reduces endogenous levels: Effect on inflammatory bowel disease
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Laura Hammer, Stacia Furtado, Edith Mathiowitz and Dominick L Auci |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Institute of Allergy and Infectious Diseases of the National Institutes of Health under award |
5R44AI080009 |
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Corresponding Author |
Dominick L Auci, PhD, Senior Researcher, Department of Research and Development, TherapyX, 108 Biomedical Research Building, 3435 Main Street, Buffalo, NY 14214, United States. dauci@therapyxinc.com |
Key Words |
Transforming growth factor beta; All trans retinoic acid; Ulcerative colitis; Crohn’s disease; Inflammatory bowel disease; Regulatory T cells |
Core Tip |
The observations suggest a negative feedback mechanism in the gut whereby local delivery of transforming growth factor beta (TGFβ) to immune structures of the gut results in reduced local and systemic levels of the active form of TGFβ. |
Publish Date |
2020-11-06 08:18 |
Citation |
Hammer L, Furtado S, Mathiowitz E, Auci DL. Oral encapsulated transforming growth factor β1 reduces endogenous levels: Effect on inflammatory bowel disease. World J Gastrointest Pharmacol Ther 2020; 11(5): 79-22 |
URL |
https://www.wjgnet.com/2150-5349/full/v11/i5/79.htm |
DOI |
https://dx.doi.org/10.4292/wjgpt.v11.i5.79 |
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