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11/20/2020 4:04:17 AM | Browse: 408 | Download: 676
Publication Name World Journal of Gastroenterology
Manuscript ID 56606
Country/Territory Brazil
2020-05-07 03:07
Peer-Review Started
2020-05-07 03:08
To Make the First Decision
Return for Revision
2020-05-15 05:34
2020-05-28 03:05
Second Decision
2020-09-30 08:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-10-01 05:15
Articles in Press
2020-10-01 05:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-11-18 15:40
Publish the Manuscript Online
2020-11-20 04:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Lactobacillus bulgaricus inhibits colitis-associated cancer via a negative regulation of intestinal inflammation in azoxymethane/dextran sodium sulfate model
Manuscript Source Unsolicited Manuscript
All Author List Denise Sayuri Calheiros Silveira, Luciana Chain Veronez, Luís Carlos Lopes-Júnior, Elen Anatriello, Mariângela Ottoboni Brunaldi and Gabriela Pereira-da-Silva
Author(s) ORCID Number
Denise Sayuri Calheiros Silveira http://orcid.org/0000-0003-1609-2731
Luciana Chain Veronez http://orcid.org/0000-0001-8926-2186
Luís Carlos Lopes-Júnior http://orcid.org/0000-0002-2424-6510
Elen Anatriello http://orcid.org/0000-0003-0718-8969
Mariângela Ottoboni Brunaldi http://orcid.org/0000-0002-7404-6779
Gabriela Pereira-da-Silva http://orcid.org/0000-0002-6743-0553
Funding Agency and Grant Number
Funding Agency Grant Number
Brazilian National Council for Scientific and Technological Development (CNPq) 140152/2013-0
Corresponding Author Gabriela Pereira-da-Silva, BSc, MSc, PhD, Professor, Research Scientist, Department of Maternal-Infant Nursing and Public Health, University of São Paulo at Ribeirão Preto College of Nursing, Av. Bandeirantes, 3900, Ribeirão Preto 14040-902, SP, Brazil. gbisson@eerp.usp.br
Key Words Lactobacillus bulgaricus; Colitis-associated cancer; Colorectal cancer; Carcinogenesis; Probiotics; Inflammation
Core Tip Recent studies suggested that consideration of the intestinal microbiota has an essential role in carcinogenesis. Probiotic supplementation is an alternative means of favourably modulating the intestinal microbiota. In this study, we investigate the effect of Lactobacillus bulgaricus (L. bulgaricus) during the development of an experimental model of colitis-associated colon cancer. Our results evidence an anti-inflammatory role and consequent antitumor effect of L. bulgaricus on colitis-associated cancer that may be used as a promising tool for the prevention and treatment of colitis-associated cancer.
Publish Date 2020-11-20 04:04
Citation Silveira DSC, Veronez LC, Lopes-Júnior LC, Anatriello E, Brunaldi MO, Pereira-da-Silva G. Lactobacillus bulgaricus inhibits colitis-associated cancer via a negative regulation of intestinal inflammation in azoxymethane/dextran sodium sulfate model. World J Gastroenterol 2020; 26(43): 6782-6794
URL https://www.wjgnet.com/1007-9327/full/v26/i43/6782.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i43.6782
Full Article (PDF) WJG-26-6782.pdf
Full Article (Word) WJG-26-6782.docx
Manuscript File 56606_Auto_Edited.docx
Answering Reviewers 56606-Answering reviewers.pdf
Audio Core Tip 56606-Audio core tip.mp3
Biostatistics Review Certificate 56606-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 56606-Conflict-of-interest statement.pdf
Copyright License Agreement 56606-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 56606-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 56606-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 56606-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 56606-Language certificate.pdf
Supplementary Material 56606-Supplementary material.pdf
Peer-review Report 56606-Peer-review(s).pdf
Scientific Misconduct Check 56606-Bing-Yan JP-1.png
Scientific Misconduct Check 56606-Scientific misconduct check.pdf
Scientific Editor Work List 56606-Scientific editor work list.pdf