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Articles Published Processes
9/4/2020 7:25:49 AM | Browse: 747 | Download: 1514
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Received |
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2020-05-19 04:23 |
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Peer-Review Started |
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2020-05-19 04:23 |
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To Make the First Decision |
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Return for Revision |
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2020-07-29 05:03 |
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Revised |
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2020-08-03 05:09 |
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Second Decision |
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2020-08-25 00:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-08-25 22:40 |
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Articles in Press |
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2020-08-25 22:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-09-01 09:08 |
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Publish the Manuscript Online |
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2020-09-04 07:25 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Effects of denosumab treatment in chronic liver disease patients with osteoporosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chisato Saeki, Mitsuru Saito, Tsunekazu Oikawa, Masanori Nakano, Yuichi Torisu, Masayuki Saruta and Akihito Tsubota |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Chisato Saeki, MD, PhD, Doctor, Doctor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 1058461, Japan. chisato@jikei.ac.jp |
| Key Words |
Chronic liver disease; Denosumab; Osteoporosis; Bone mineral density; Bone turnover; Bone quality |
| Core Tip |
Osteoporosis is a common complication that causes fragility fractures and reduces health-related quality of life in patients with chronic liver disease. Denosumab treatment significantly increased bone mineral density at the lumbar spine, femoral neck, and total hip; suppressed bone turnover markers; and improved a bone quality marker at 12 mo, regardless of differences in baseline characteristics. No patients experienced fractures and adverse events, except for transient hypocalcemia. Denosumab treatment is safe and beneficial treatment option for osteoporosis in chronic liver disease patients. |
| Publish Date |
2020-09-04 07:25 |
| Citation |
Saeki C, Saito M, Oikawa T, Nakano M, Torisu Y, Saruta M, Tsubota A. Effects of denosumab treatment in chronic liver disease patients with osteoporosis. World J Gastroenterol 2020; 26(33): 4960-4971 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i33/4960.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i33.4960 |
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