Publication Name	World Journal of Gastroenterology
Manuscript ID	5680
Country	Italy

Received	2013-09-22 11:49
Peer-Review Started	2013-09-24 10:18
To Make the First Decision	2013-10-14 21:26
Return for Revision	2013-10-20 21:34
Revised	2013-10-31 01:16
Second Decision	2014-01-06 18:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-06 19:02
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-23 11:59
Publish the Manuscript Online	2014-03-27 12:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Systemic therapy of hepatocellular carcinoma: Current status and future perspectives
Manuscript Source	Invited Manuscript
All Author List	Domenico Germano and Bruno Daniele
Funding Agency and Grant Number	Funding Agency Grant Number consulting and lecture fees from Bayer, Daiichi Sankyo and Novartis to Daniele B
Corresponding Author	Domenico Germano, MD, Oncology Unit, A.O. “G. Rummo”, Via dell’Angelo, 1, 82100 Benevento, Italy. domgerm@libero.it
Key Words	Hepatocellular Carcinoma; Molecular agents; Targheted therapy; Sorafenib
Core Tip	Many molecularly targeted agents that inhibit angiogenesis, epidermal growth factor receptor, and mammalian target of rapamycin are at different stages of clinical development in advanced hepatocellular carcinoma. Future research should continue to unravel the mechanism of hepatocarcinogenesis and to identify key relevant molecular targets for therapeutic intervention.
Publish Date	2014-03-27 12:04
Citation	Germano D, Daniele B. Systemic therapy of hepatocellular carcinoma: Current status and future perspectives. World J Gastroenterol 2014; 20(12): 3087-3099
URL	http://www.wjgnet.com/1007-9327/full/v20/i12/3087.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i12.3087

Full Article (PDF)	WJG-20-3087.pdf
Full Article (Word)	WJG-20-3087.doc
Manuscript File	5680-Review.doc
Answering Reviewers	5680-Answering reviewers.pdf
Copyright License Agreement	5680-Copyright assignment.pdf
Peer-review Report	5680-Peer reviewer(s).pdf
Scientific Editor Work List	5680-Scientific editor work list.doc