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9/9/2020 11:11:52 AM | Browse: 35 | Download: 44
Publication Name World Journal of Gastroenterology
Manuscript ID 56819
Country/Territory Japan
Received
2020-05-19 09:32
Peer-Review Started
2020-05-19 09:33
To Make the First Decision
Return for Revision
2020-06-20 00:27
Revised
2020-06-30 02:46
Second Decision
2020-08-13 11:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-13 21:13
Articles in Press
2020-08-13 21:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-09-09 00:56
Publish the Manuscript Online
2020-09-09 11:11
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Acupuncture improved lipid metabolism by regulating intestinal absorption in mice
Manuscript Source Unsolicited Manuscript
All Author List Jia Han, Xin Guo, Xiang-Jin Meng, Jing Zhang, Reimon Yamaguchi, Yoshiharu Motoo and Sohsuke Yamada
ORCID
Author(s) ORCID Number
Jia Han http://orcid.org/0000-0003-0108-996X
Xin Guo http://orcid.org/0000-0002-5072-7000
Xiang-Jin Meng http://orcid.org/0000-0002-0530-0921
Jing Zhang http://orcid.org/0000-0002-9900-5009
Reimon Yamaguchi http://orcid.org/0000-0001-7084-1567
Yoshiharu Motoo http://orcid.org/0000-0002-0776-6434
Sohsuke Yamada http://orcid.org/0000-0003-2662-0024
Funding Agency and Grant Number
Funding Agency Grant Number
Grants-in-Aid for Scientific Research 19K16783
Ministry of Education, Culture, Sports, Science and Technology, Tokyo, Japan 20K07454,20K17363
Grant for Promoted Research from Kanazawa Medical University S2018-6
Corresponding author Xin Guo, PhD, Doctor, Department of Pathology and Laboratory Medicine, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Kahoku, Ishikawa 920-0293, Japan. tianqi11211216@yahoo.co.jp
Key Words Acupuncture; Non-alcoholic fatty liver disease; Small intestine; Lipid metabolism; Apolipoproteins;
Core Tip In the present study, our experimental data showed that acupuncture treatment suppressed high-fat-induced body weight gain, reduced the accumulation of intra-abdominal fat, inhibited lipid absorption in the small intestine and downregulated the blood lipid level in mice with non-alcoholic fatty liver disease, suggesting that acupuncture potentially had variable beneficial effects in improving the lipid metabolism in the presence of abnormal liver metabolism. Furthermore, we also found more fat deposition in the intestinal epithelium with the decreased expression of some intestinal apolipoproteins in acupuncture-treated mice, suggesting that acupuncture may suppress lipid absorption by downregulating the expression of apolipoproteins in the small intestine.
Publish Date 2020-09-09 11:11
Citation Han J, Guo X, Meng XJ, Zhang J, Yamaguchi R, Motoo Y, Yamada S. Acupuncture improved lipid metabolism by regulating intestinal absorption in mice. World J Gastroenterol 2020; 26(34): 5118-5129
Url https://www.wjgnet.com/1007-9327/full/v26/i34/5118.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i34.5118
Full Article (PDF) WJG-26-5118.pdf
Full Article (Word) WJG-26-5118.docx
Manuscript File 56819-Review.docx
Answering Reviewers 56819-Answering reviewers.pdf
Audio Core Tip 56819-Audio core tip.mp3
Biostatistics Review Certificate 56819-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 56819-Conflict-of-interest statement.pdf
Copyright License Agreement 56819-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 56819-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 56819-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 56819-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 56819-Language certificate.pdf
Video 56819-Video.mp4
Supplementary Material 56819-Supplementary material.pdf
Peer-review Report 56819-Peer-review(s).pdf
Scientific Misconduct Check 56819-Bing-Liu M-1.png
Scientific Misconduct Check 56819-Scientific misconduct check.pdf
Scientific Editor Work List 56819-Scientific editor work list.pdf