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11/6/2020 7:36:12 AM | Browse: 1324 | Download: 3015
Publication Name World Journal of Gastroenterology
Manuscript ID 56911
Country China
Received
2020-05-19 10:49
Peer-Review Started
2020-05-19 10:49
First Decision by Editorial Office Director
2020-07-29 04:34
Return for Revision
2020-07-29 04:34
Revised
2020-07-30 05:13
Publication Fee Transferred
Second Decision by Editor
2020-08-28 12:18
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2020-08-29 02:16
Articles in Press
2020-08-29 02:16
Edit the Manuscript by Language Editor
2020-09-16 09:07
Typeset the Manuscript
2020-11-05 01:40
Publish the Manuscript Online
2020-11-06 07:36
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Dihydromyricetin ameliorates chronic liver injury by reducing pyroptosis
Manuscript Source Unsolicited Manuscript
All Author List Quan-Cheng Cheng, Jing Fan, Xin-Wei Deng, Huai-Cun Liu, Hui-Ru Ding, Xuan Fang, Jian-Wei Wang, Chun-Hua Chen and Wei-Guang Zhang
ORCID
Author(s) ORCID Number
Quan-Cheng Cheng http://orcid.org/0000-0002-3527-252X
Jing Fan http://orcid.org/0000-0003-4604-401X
Xin-Wei Deng http://orcid.org/0000-0002-3939-2713
Huai-Cun Liu http://orcid.org/0000-0002-5157-3840
Hui-Ru Ding http://orcid.org/0000-0003-1798-5806
Xuan Fang http://orcid.org/0000-0002-7705-6139
Jian-Wei Wang http://orcid.org/0000-0002-7349-0325
Chun-Hua Chen http://orcid.org/0000-0002-8502-8189
Wei-Guang Zhang http://orcid.org/0000-0001-5055-4907
Funding Agency and Grant Number
Funding Agency Grant Number
Beijing Municipal Natural Science Foundation 7162098
National Natural Science Foundation of China 81873769
Corresponding Author Wei-Guang Zhang, MD, PhD, Professor, Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Peking University Health Science Center, No. 38 Xueyuan Road, Haidian District, Beijing 100191, China. zhangwg@bjmu.edu.cn
Key Words Chronic liver injury; Dihydromyricetin; Pyroptosis; Carbon tetrachloride; Pathogenesis; Steatosis
Core Tip We established a model of chronic liver injury (CLI) in mice by subcutaneous injection of CCL4 into the back, demonstrating the effect of dihydromyricetin on improving CLI in terms of morphology and serum level, and verifying the activation of pyroptosis in CLI and the regulation of pyroptosis by dihydromyricetin in terms of protein level and mRNA level respectively.
Publish Date 2020-11-06 07:36
Citation Cheng QC, Fan J, Deng XW, Liu HC, Ding HR, Fang X, Wang JW, Chen CH, Zhang WG. Dihydromyricetin ameliorates chronic liver injury by reducing pyroptosis. World J Gastroenterol 2020; 26(41): 6346-6360
URL https://www.wjgnet.com/1007-9327/full/v26/i41/6346.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i41.6346
Full Article (PDF) WJG-26-6346.pdf
Full Article (Word) WJG-26-6346.docx