Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	5692
Country	United States

Received	2013-09-22 13:59
Peer-Review Started	2013-09-22 19:44
To Make the First Decision	2013-10-14 14:19
Return for Revision	2013-10-20 23:36
Revised	2013-12-19 04:34
Second Decision	2014-04-29 08:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-29 08:42
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-12 20:36
Publish the Manuscript Online	2014-05-20 12:16

ISSN	1948-5190 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Meta-Analysis
Article Title	Early precut sphincterotomy and the risk of endoscopic retrograde cholangiopancreatography related complications: An updated meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Udayakumar Navaneethan, Rajesh Konjeti, Preethi GK Venkatesh, Madhusudhan R Sanaka and Mansour A Parsi
Funding Agency and Grant Number
Corresponding Author	Mansour A Parsi, MD, MPH, Head, Section for Advanced Endoscopy and Pancreatobiliary Disorders, Department of Gastroenterology, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, United States. parsim@ccf.org
Key Words	Post-cholangiopancreatography pancreatitis; Pre-cut sphincterotomy; Persistent attempts; Meta analysis
Core Tip	Selective cannulation of the bile duct remains the limiting step in therapeutic post-endoscopic retrograde cholangiopancreatography (ERCP). Greater than 90% of cannulation is achieved through standard techniques. In 10% of patients, cannulation is difficult and requires additional techniques such as pre-cut sphincterotomy. Early use of pre-cut sphincterotomy is suggested as a means to prevent excessive and repetitive papillary trauma which may in turn increase the risk of post-ERCP pancreatitis. The use of pre-cut sphincterotomy has been considered to increase risk of post-ERCP complications, in particular post-ERCP pancreatitis. We studied the literature on the use of pre-cut sphincterotomy in biliary access. Our meta-analysis showed that pre-cut sphincterotomy and persistent attempts at cannulation are comparable in terms of overall complication rates including post-ERCP pancreatitis. Early pre-cut implementation does not increase PEP complications.
Publish Date	2014-05-20 12:16
Citation	Navaneethan U, Konjeti R, Venkatesh PGK, Sanaka MR, Parsi MA. Early precut sphincterotomy and the risk of endoscopic retrograde cholangiopancreatography related complications: An updated meta-analysis. World J Gastrointest Endosc 2014; 6(5): 200-208
URL	http://www.wjgnet.com/1948-5190/full/v6/i5/200.htm
DOI	http://dx.doi.org/10.4253/wjge.v6.i5.200

Full Article (PDF)	WJGE-6-200.pdf
Manuscript File	5692-Review.doc
Answering Reviewers	5692-Answering reviewers.pdf
Copyright License Agreement	5692-Copyright assignment.pdf
Peer-review Report	5692-Peer reviewer(s).pdf
Scientific Editor Work List	5692-Scientific editor work list.doc