Publication Name	World Journal of Gastroenterology
Manuscript ID	5701
Country	Italy

Received	2013-09-22 14:51
Peer-Review Started	2013-09-22 18:25
To Make the First Decision	2014-01-15 19:54
Return for Revision	2013-10-28 11:43
Revised	2014-04-22 00:00
Second Decision	2014-06-13 11:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-13 12:53
Articles in Press	2014-06-13 12:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-07-07 09:32
Typeset the Manuscript	2014-09-02 10:58
Publish the Manuscript Online	2014-10-07 17:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Topic Highlights
Article Title	Crohn's disease and growth deficiency in children and adolescents
Manuscript Source	Invited Manuscript
All Author List	Marco Gasparetto and Graziella Guariso
Funding Agency and Grant Number
Corresponding Author	Marco Gasparetto, MD, Department of Women’s and Children’s Health, Unit for Pediatric Gastroenterology, Digestive Endoscopy, Hepatology and Care of Children with Liver Transplants, Padova University Hospital, Via Giustiniani 3, 35128 Padova, Italy. markgasp@gmail.com
Key Words	Bone health; Enteral nutrition; Growth; Height; Pediatric inflammatory bowel disease; Pediatric Crohn’s disease; Linear growth; Pubertal growth; Vitamin D; Weight loss
Core Tip	This review focuses on current evidence for managing growth issues in children diagnosed with Crohn’s disease. Long-term control of active inflammation and an adequate intake of nutrients are both essential in promoting puberty. Exclusive enteral nutrition has a key role, as it induces disease remission and improves nutritional status. The early introduction of immunosuppressants or biologics may be justified in children to achieve disease remission and enable their growth to catch up, ideally before puberty. Recent evidence suggests that recombinant growth factor therapy is effective in improving short-term linear growth.
Publish Date	2014-10-07 17:32
Citation	Gasparetto M, Guariso G. Crohn’s disease and growth deficiency in children and adolescents. World J Gastroenterol 2014; 20(37): 13219-13233
URL	http://www.wjgnet.com/1007-9327/full/v20/i37/13219.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i37.13219

Full Article (PDF)	WJG-20-13219.pdf
Full Article (Word)	WJG-20-13219.doc
Manuscript File	5701-Review.docx
Answering Reviewers	5701-Answering reviewers.pdf
Copyright License Agreement	5701-Copyright assignment.pdf
Peer-review Report	5701-Peer review.pdf
Scientific Misconduct Check	5701-CorssCheck.jpg
Scientific Editor Work List	5701-Scientific editor work list.pdf