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9/22/2020 3:17:13 AM | Browse: 585 | Download: 1033
Publication Name World Journal of Clinical Cases
Manuscript ID 57030
Country/Territory South Korea
Received
2020-05-27 23:58
Peer-Review Started
2020-05-27 23:59
To Make the First Decision
Return for Revision
2020-06-13 04:13
Revised
2020-08-11 10:37
Second Decision
2020-08-21 12:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-21 21:04
Articles in Press
2020-08-21 21:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-08-26 13:37
Typeset the Manuscript
2020-09-16 13:59
Publish the Manuscript Online
2020-09-22 03:17
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title First-line chemotherapy in very elderly patients with metastatic pancreatic cancer: Gemcitabine monotherapy vs combination chemotherapy
Manuscript Source Unsolicited Manuscript
All Author List Sung Yong Han, Dong Uk Kim, Young Mi Seol, Suk Kim, Nam Kyung Lee, Seung Baek Hong and Hyung-Il Seo
ORCID
Author(s) ORCID Number
Sung Yong Han http://orcid.org/0000-0002-0256-9781
Dong Uk Kim http://orcid.org/0000-0002-7208-7753
Young Mi Seol http://orcid.org/0000-0002-4627-5275
Suk Kim http://orcid.org/0000-0003-3268-1763
Nam Kyung Lee http://orcid.org/0000-0003-1972-2719
Seung Baek Hong http://orcid.org/0000-0002-1731-0430
Hyung-Il Seo http://orcid.org/0000-0002-4132-7662
Funding Agency and Grant Number
Funding Agency Grant Number
the National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT) 2018R1C1B5086234
Corresponding Author Young Mi Seol, MD, PhD, Assistant Professor, Department of Internal Medicine and Biomedical Research Institute, Division of Hematology-Oncology, Pusan National University Hospital, Gudeok ro 179, seo-gu, Busan 49241, South Korea. seol2100@hanmail.net
Key Words Combination chemotherapy; Gemcitabine;; Pancreatic cancer; Elderly; Ductal carcinoma; Adverse drug event
Core Tip Combination therapy (gemcitabine plus nab-paclitaxel and FOLFIRINOX) is known to be more effective than gemcitabine monotherapy in pancreatic cancer patients over 65 years of age. However, the effect in the very elderly (age 75 and over) is not well known. Our retrospective study aims to compare the efficacies of gemcitabine mono versus combination therapy in very elderly pancreatic cancer patients. Our data showed that in elderly patients, combination therapy was more efficient compared to gemcitabine monotherapy. However, gemcitabine monotherapy may be a better option for managing metastatic pancreatic cancer in very elderly patients compared to combination therapy.
Publish Date 2020-09-22 03:17
Citation Han SY, Kim DU, Seol YM, Kim S, Lee NK, Hong SB, Seo HI. First-line chemotherapy in very elderly patients with metastatic pancreatic cancer: Gemcitabine monotherapy vs combination chemotherapy. World J Clin Cases 2020; 8(18): 4022-4033
URL https://www.wjgnet.com/2307-8960/full/v8/i18/4022.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i18.4022
Full Article (PDF) WJCC-8-4022.pdf
Full Article (Word) WJCC-8-4022.docx
Manuscript File 57030-Review-Filipodia.docx
Answering Reviewers 57030-Answering reviewers.pdf
Audio Core Tip 57030-Audio core tip.mp3
Biostatistics Review Certificate 57030-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57030-Conflict-of-interest statement.pdf
Copyright License Agreement 57030-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57030-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 57030-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57030-Language certificate.pdf
Supplementary Material 57030-Supplementary material.pdf
Peer-review Report 57030-Peer-review(s).pdf
Scientific Misconduct Check 57030-Scientific misconduct check.pdf
Scientific Editor Work List 57030-Scientific editor work list.pdf