Publication Name	World Journal of Clinical Cases
Manuscript ID	57187
Country	Japan

Received	2020-06-03 05:08
Peer-Review Started	2020-06-03 05:09
To Make the First Decision
Return for Revision	2020-09-13 14:31
Revised	2020-09-22 07:53
Second Decision	2020-10-10 10:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-10-13 04:54
Articles in Press	2020-10-13 04:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-11-20 01:13
Publish the Manuscript Online	2020-11-25 14:44

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Azacitidine decreases reactive oxygen species production in peripheral white blood cells: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Hidekazu Hasunuma, Naomi Shimizu, Hiromitsu Yokota and Ichiro Tatsuno
ORCID	Author(s) ORCID Number Hidekazu Hasunuma http://orcid.org/0000-0003-0771-8659 Naomi Shimizu http://orcid.org/0000-0001-8295-8893 Hiromitsu Yokota http://orcid.org/0000-0001-9891-975X Ichiro Tatsuno http://orcid.org/0000-0002-7200-7952
Funding Agency and Grant Number
Corresponding Author	Naomi Shimizu, MD, PhD, Assistant Professor, Department of Hematology, Toho University Medical Center Sakura Hospital, No. 564-1, Shimoshizu, Sakura 2858741, Japan. naomis-cib@umin.ac.jp
Key Words	Myelodysplastic syndrome; Reactive oxygen species; Diacron-reactive oxygen metabolites; Ferritin; Azacitidine; Case report
Core Tip	Accumulation of reactive oxygen species (ROS) contributes to the development and progression of cancer. We reported a case of myelodysplastic syndrome that showed decreased ROS production by white blood cells, decreased diacron-reactive oxygen metabolites (d-ROMs) in serum and decreased Wilms’ tumor 1 after azacitidine therapy, which can improve hematopoiesis by decreasing ROS and d-ROMs production.
Publish Date	2020-11-25 14:44
Citation	Hasunuma H, Shimizu N, Yokota H, Tatsuno I. Azacitidine decreases reactive oxygen species production in peripheral white blood cells: A case report. World J Clin Cases 2020; 8(22): 5657-5662
URL	https://www.wjgnet.com/2307-8960/full/v8/i22/5657.htm
DOI	https://dx.doi.org/10.12998/wjcc.v8.i22.5657

Full Article (PDF)	WJCC-8-5657.pdf
Full Article (Word)	WJCC-8-5657.docx
Manuscript File	57187_Auto_Edited.docx
Answering Reviewers	57187-Answering reviewers.pdf
Audio Core Tip	57187-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	57187-Conflict-of-interest statement.pdf
Copyright License Agreement	57187-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	57187-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	57187-Language certificate.pdf
Peer-review Report	57187-Peer-review(s).pdf
Scientific Misconduct Check	57187-Bing-Wang JL-1.jpg
Scientific Misconduct Check	57187-Scientific misconduct check.pdf
Scientific Editor Work List	57187-Scientific editor work list.pdf
CrossCheck Report	57187-CrossCheck report.pdf