Publication Name	World Journal of Gastroenterology
Manuscript ID	5721
Country	United States

Received	2013-09-23 09:55
Peer-Review Started	2013-09-24 10:03
To Make the First Decision	2013-10-14 21:15
Return for Revision	2013-10-16 10:04
Revised	2013-12-18 23:29
Second Decision	2014-04-03 10:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-03 12:25
Articles in Press	2014-05-23 10:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-14 17:40
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	c-Met signaling in the development of tumorigenesis and chemoresistance: Potential applications in pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Daniel Delitto, Eva Vertes-George, Steven J Hughes, Kevin E Behrns and Jose G Trevino
Funding Agency and Grant Number
Corresponding Author	Jose G Trevino, MD, Department of Surgery, University of Florida-Gainesville, 1600 SW Archer Rd, Rm 6175, PO Box 100109, Gainesville, FL 32610, United States. jose.trevino@surgery.ufl.edu ID:00006265
Key Words	Pancreatic adenocarcinoma; c-Met; Chemoresistance; Receptor tyrosine kinase
Core Tip	As one of the leading causes of cancer-related deaths, pancreatic cancer remains elusive to our current therapeutic options. These modest advances in current therapies for pancreatic cancer have led to the recognition and development of targeted therapies toward tyrosine kinase receptors such as the c-Met receptor. In this review, we characterize the role of c-Met in the development of tumorigenesis, metastasis and chemoresistance, highlighting the potential of c-Met as a therapeutic target in pancreatic cancer.
Publish Date	2014-07-14 17:39
Citation	Delitto D, Vertes-George E, Hughes SJ, Behrns KE, Trevino JG. c-Met signaling in the development of tumorigenesis and chemoresistance: Potential applications in pancreatic cancer. World J Gastroenterol 2014; 20(26): 8458-8470
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8458.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8458

Full Article (PDF)	WJG-20-8458.pdf
Full Article (Word)	WJG-20-8458.doc
Manuscript File	5721-Review.doc
Answering Reviewers	5721-Answering reviewers.pdf
Copyright License Agreement	5721-Copyright assignment.pdf
Peer-review Report	5721-Peer reviews.pdf
Scientific Editor Work List	5721-Scientific editor work list.doc