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Articles Published Processes
11/18/2020 2:20:37 PM | Browse: 632 | Download: 783
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Received |
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2020-08-05 18:21 |
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Peer-Review Started |
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2020-08-05 18:21 |
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To Make the First Decision |
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Return for Revision |
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2020-09-17 16:29 |
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Revised |
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2020-10-01 02:59 |
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Second Decision |
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2020-10-16 11:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-19 20:21 |
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Articles in Press |
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2020-10-19 20:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-11-05 11:17 |
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Publish the Manuscript Online |
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2020-11-18 14:20 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Chemotherapy rechallenge in metastatic colon cancer: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tejaswini Parlapalle Reddy, Usman Khan, Ethan Alexander Burns and Maen Abdelrahim |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maen Abdelrahim, BPharm, MD, PhD, Assistant Professor, Section of GI Oncology, Department of Medical Oncology, Houston Methodist Cancer Center. Cockrell Center of Advanced Therapeutics Phase I Program, Houston Methodist Research Institute and Weill Cornell Medical College, 6445 Main ST Fl 24, Houston, TX 77030, United States. mabdelrahim@houstonmethodist.org |
| Key Words |
Metastatic colorectal cancer; Rechallenge therapy; Treatment holiday; Oxaliplatin; Irinotecan; Case report |
| Core Tip |
Despite advances in therapeutic strategies, colorectal cancer (CRC) remains a deadly disease. There are limited options for patients with chemo-refractory mCRC. We present a case of a patient with heavily treated metastatic colorectal cancer (mCRC) that was responsive to oxaliplatin-based rechallenge therapy. Oxaliplatin rechallenge therapy provided this patient with a ten-month survival benefit, marked improvement in his clinical condition, performance status, and quality of life. This case highlights the importance of considering rechallenge therapy in patients with chemo-refractory mCRC. Monitoring for oxaliplatin-associated peripheral sensory neuropathy should be considered for patients who qualify for oxaliplatin rechallenge therapy. |
| Publish Date |
2020-11-18 14:20 |
| Citation |
Reddy TP, Khan U, Burns EA, Abdelrahim M. Chemotherapy rechallenge in metastatic colon cancer: A case report. World J Clin Oncol 2020; 11(11): 959-967 |
| URL |
https://www.wjgnet.com/2218-4333/full/v11/i11/959.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v11.i11.959 |
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