Publication Name	World Journal of Gastroenterology
Manuscript ID	5736
Country	Italy

Received	2013-09-25 08:36
Peer-Review Started	2013-09-25 11:31
First Decision by Editorial Office Director
Return for Revision	2013-10-23 09:45
Revised	2013-11-08 01:54
Publication Fee Transferred
Second Decision by Editor	2013-12-13 13:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-12-13 14:47
Articles in Press
Edit the Manuscript by Language Editor	2014-01-17 16:05
Typeset the Manuscript	2014-03-04 18:58
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pathology
Manuscript Type	Topic Highlights
Article Title	Histopathological evaluation of recurrent hepatitis C after liver transplantation: A review
Manuscript Source	Invited Manuscript
All Author List	Francesco Vasuri, Deborah Malvi, Elisa Gruppioni, Walter F Grigioni and Antonia D’Errico-Grigioni
Funding Agency and Grant Number
Corresponding Author	Walter F Grigioni, MD, “F. Addarii” Institute of Oncology and Transplant Pathology, S. Orsola-Malpighi Hospital, Bologna University, V.le Ercolani 4/2, 40138 Bologna, Italy. franco.grigioni@aosp.bo.it
Key Words	Hepatitis C virus; Histopathology; Immunohistochemistry; Orthotopic liver transplantation; Recurrent hepatitis C; Polymerase chain reaction
Core Tip	Recently, tissue hepatitis C virus (HCV) RNA quantitation by means of reverse transcription-polymerase chain reaction has been largely used in the early post-orthotopic liver transplantation (OLT) phases, especially in the differential diagnosis of recurrent hepatitis C vs mild acute rejection, replacing immunohistochemistry in some laboratories. Nevertheless, the importance of tissue HCV RNA quantitation in the long post-OLT term has not been clarified yet. The suitability and usefulness of protocol biopsies are still debated: protocol biopsies may be necessary in order to answer other open questions, such as the significance of plasma cell infiltrate in HCV-positive allografts, the prognostic weight of HCV-induced steatosis, and the impact of donor age in recurrent hepatitis C.
Publish Date	2014-03-18 14:14
Citation	Vasuri F, Malvi D, Gruppioni E, Grigioni WF, D’Errico-Grigioni A. Histopathological evaluation of recurrent hepatitis C after liver transplantation: A review. World J Gastroenterol 2014; 20(11): 2810-2824
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/2810.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.2810

Full Article (PDF)	WJG-20-2810.pdf
Full Article (Word)	WJG-20-2810.doc
Manuscript File	5736-Review.doc
Answering Reviewers	5736-Answering reviewers.pdf
Copyright License Agreement	5736-Copyright assignment.pdf
Peer-review Report	5736-Peer reviews.pdf
Scientific Editor Work List	5736-Scientific editor work list.doc