Publication Name	World Journal of Gastroenterology
Manuscript ID	5751
Country	Thailand

Received	2013-09-25 10:20
Peer-Review Started	2013-09-25 16:15
To Make the First Decision	2013-12-26 10:57
Return for Revision	2013-12-27 12:17
Revised	2014-01-06 14:52
Second Decision	2014-01-20 17:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 18:20
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-03 17:20
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Hepatitis C virus genotype 6: Virology, epidemiology, genetic variation and clinical implication
Manuscript Source	Invited Manuscript
All Author List	Vo Duy Thong, Srunthron Akkarathamrongsin, Kittiyod Poovorawan, Pisit Tangkijvanich and Yong Poovorawan
Funding Agency and Grant Number	Funding Agency Grant Number Research Unit of Hepatitis and Liver Cancer, Chulalongkorn University Scholarship Program for Neighboring Countries, Chulalongkorn University Higher Education Research Promotion and National Research University Project of Thailand HR1155A-55 Thailand Research Fund DPG5480002 Thailand Research Fund BRG5580005 Office of the Commission on Higher Education Center of Excellence in Clinical Virology, Chulalongkorn University Integrated Innovation Academic Center IIAC Chulalongkorn University Centenary Academic Development Project CU56-HR01 Ratchadaphiseksomphot Endowment Fund of Chulalongkorn University RES560530093 King Chulalongkorn Memorial Hospital
Corresponding Author	Yong Poovorawan, MD, Professor, Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. yong.p@chula.ac.th
Key Words	Hepatitis C virus; Genotype 6; Epidemiology; Clinical; Treatment
Core Tip	Hepatitis C virus (HCV) genotype 6 is restricted to South China, South-East Asia, and it is occasionally found in migrant patients from endemic countries. Treatment response rates are lower than those of genotype 3 but higher than those of genotype 1. Based on current evidence, the optimal treatment duration of HCV-6 should be 48 wk. Shortened treatment duration of 24 wk could be sufficient in patients with low pretreatment viral load who achieve rapid virological response. The development of direct-acting antiviral agents is ongoing, and they give high response rate when combined with standard therapy. We review the epidemiology, classification, diagnosis and treatment.
Publish Date	2014-03-18 14:14
Citation	Thong VD, Akkarathamrongsin S, Poovorawan K, Tangkijvanich P, Poovorawan Y. Hepatitis C virus genotype 6: Virology, epidemiology, genetic variation and clinical implication. World J Gastroenterol 2014; 20(11): 2927-2940
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/2927.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.2927

Full Article (PDF)	WJG-20-2927.pdf
Full Article (Word)	WJG-20-2927.doc
Manuscript File	5751-Review.doc
Answering Reviewers	5751-Answering reviewers.pdf
Copyright License Agreement	5751-Copyright assignment.pdf
Peer-review Report	5751-Peer reviews.pdf
Scientific Editor Work List	5751-Scientific editor work list.doc