Publication Name	World Journal of Gastroenterology
Manuscript ID	5758
Country	South Korea

Received	2013-09-25 10:47
Peer-Review Started	2013-09-25 16:32
To Make the First Decision	2013-10-22 16:40
Return for Revision	2013-10-23 10:13
Revised	2013-11-15 15:40
Second Decision	2013-12-13 13:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-13 14:48
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-12 17:21
Publish the Manuscript Online	2014-02-26 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Minireviews
Article Title	Targeted therapy in gastric cancer: Personalizing cancer treatment based on patient genome
Manuscript Source	Invited Manuscript
All Author List	Sun Min Lim, Jae Yun Lim and Jae Yong Cho
Funding Agency and Grant Number
Corresponding Author	Dr. Jae Yong Cho, MD, PhD, Department of Medical Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, 712 Eonjuro, Gangnam-gu, Seoul 135-720, South Korea. chojy@yuhs.ac
Key Words	Gastric cancer; Targeted therapy; Biomarker; Microarray; Sequencing
Core Tip	Understanding the molecular mechanisms governing carcinogenesis, progression and prognosis of gastric cancer is a prerequisite for development of effective management strategies. Analysis of genomic and proteomic expression profiles of oncogenic signaling pathways have revealed different molecular subtypes of gastric cancer. Development of personalized cancer therapy regimens will specifically target aberrations that drive tumor growth and survival. Therefore, identifying and administering the appropriate drug based on genetic profiling will improve clinical outcomes and decrease toxicity. We anticipate that identification of novel cancer targets will further aid in understanding of cancer heterogeneity and in refinement of personalized therapeutic strategies.
Publish Date	2014-02-26 11:18
Citation	Lim SM, Lim JY, Cho JY. Targeted therapy in gastric cancer: Personalizing cancer treatment based on patient genome. World J Gastroenterol 2014; 20(8): 2042-2050
URL	http://www.wjgnet.com/1007-9327/full/v20/i8/2042.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i8.2042

Full Article (PDF)	WJG-20-2042.pdf
Full Article (Word)	WJG-20-2042.doc
Manuscript File	5758-Review.doc
Answering Reviewers	5758-Answering reviewers.pdf
Copyright License Agreement	5758-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5758-Language certificate.pdf
Peer-review Report	5758-Peer reviews.pdf
Scientific Editor Work List	5758-Scientific editor work list.doc