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Articles Published Processes
12/27/2020 5:30:53 AM | Browse: 797 | Download: 1387
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Received |
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2020-06-16 04:00 |
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Peer-Review Started |
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2020-06-16 04:01 |
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To Make the First Decision |
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Return for Revision |
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2020-09-18 16:57 |
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Revised |
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2020-09-28 03:45 |
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Second Decision |
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2020-10-23 10:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-26 16:54 |
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Articles in Press |
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2020-10-26 16:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-13 04:02 |
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Typeset the Manuscript |
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2020-12-24 08:00 |
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Publish the Manuscript Online |
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2020-12-27 05:30 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Review |
| Article Title |
Effect of metformin on stem cells: Molecular mechanism and clinical prospect
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lin-Li Jiang and Lei Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81670951 |
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| Corresponding Author |
Lei Liu, MD, PhD, Professor, Department of State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Oral and Maxillofacial Surgery Department, West China Hospital of Stomatology, Sichuan University, No. 14 Section 3 Renmin South Road, Chengdu 610041, Sichuan Province, China. drliulei@163.com |
| Key Words |
Metformin; Stem cells; Differentiation; Anti-aging; Anti-cancer; Mechanism |
| Core Tip |
The effect of metformin on stem cells is quickly gaining attention. Because metformin modulates various physiological activities and pathological changes via targeting stem cells. Emerging studies suggest that metformin has broad prospects in the fields of stem cell medicine, gerontology, regenerative medicine, and cancer therapy, etc. In this review, we summarize the effects of metformin on stem cells and provide an overview of its molecular mechanisms and clinical prospects. |
| Publish Date |
2020-12-27 05:30 |
| Citation |
Jiang LL, Liu L. Effect of metformin on stem cells: Molecular mechanism and clinical prospect. World J Stem Cells 2020; 12(12): 1455-1473 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i12/1455.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i12.1455 |
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