Publication Name	World Journal of Gastroenterology
Manuscript ID	5764
Country	China

Received	2013-09-25 13:08
Peer-Review Started	2013-09-25 16:42
To Make the First Decision	2013-10-14 21:13
Return for Revision	2013-10-16 13:37
Revised	2013-11-06 14:08
Second Decision	2013-12-13 13:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-13 14:49
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-01-11 18:45
Typeset the Manuscript	2014-02-13 10:24
Publish the Manuscript Online	2014-02-26 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Cancer stem cell markers correlate with early recurrence and survival in hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Zhe Guo, Le-Qun Li, Jing-Hang Jiang, Chao Ou, Li-Xia Zeng and Bang-De Xiang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81260331 National Science and Technology Major Project of the Ministry of Science and Technology of China 2012ZX10002010001009 Innovation Project of Guangxi Graduate Education 2011105981002M232
Corresponding Author	Bang-De Xiang, PhD, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, He Di Rd. 71, Nanning 530021, Guangxi Zhuang Autonomous Region, China. xiaopushu-213@163.com
Key Words	Hepatocellular carcinoma; Cancer stem cells; CD133; CD90; Epithelial cell adhesion molecule
Core Tip	Cancer stem cells have been proposed as the cells responsible for initiating tumor formation, recurrence and metastasis, and liver cancer stem cells have been found to carry the surface markers CD133, CD90, and epithelial cell adhesion molecule (EpCAM). This paper addresses the clinical impact of CD133, CD90, and EpCAM in propensity score-matched patients with hepatocellular carcinoma. Our findings revealed that expression of CD133, CD90, and EpCAM may be linked to hepatocellular carcinoma (HCC) tumor onset and/or progression. In addition, EpCAM expression is associated with shorter survival time, while CD90 expression is associated with early HCC recurrence.
Publish Date	2014-02-26 11:18
Citation	Guo Z, Li LQ, Jiang JH, Ou C, Zeng LX, Xiang BD. Cancer stem cell markers correlate with early recurrence and survival in hepatocellular carcinoma. World J Gastroenterol 2014; 20(8): 2098-2106
URL	http://www.wjgnet.com/1007-9327/full/v20/i8/2098.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i8.2098

Full Article (PDF)	WJG-20-2098.pdf
Full Article (Word)	WJG-20-2098.doc
Manuscript File	5764-Review.docx
Answering Reviewers	5764-Answering reviewers.pdf
Copyright License Agreement	5764-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5764-Language certificate.pdf
Peer-review Report	5764-Peer reviews.pdf
Scientific Editor Work List	5764-Scientific editor work list.doc