| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Rehabilitation |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Endothelial progenitor cells mobilization after maximal exercise according to heart failure severity
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Christos Kourek, Eleftherios Karatzanos, Katherina Psarra, Georgios Georgiopoulos, Dimitrios Delis, Vasiliki Linardatou, Gerasimos Gavrielatos, Costas Papadopoulos, Serafim Nanas and Stavros Dimopoulos |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National and Kapodistrian University of Athens |
|
| Greece and the European Union (European Social Fund-ESF) through the Operational Programme «Human Resources Development, Education and Lifelong Learning» in the context of the project “Strengthening Human Resources Research Potential via Doctorate Research” |
MIS-5000432 |
|
| Corresponding Author |
Stavros Dimopoulos, MD, PhD, Doctor, Doctor, Postdoc, Research Scientist, Senior Researcher, Staff Physician, Cardiac Surgery Intensive Care Unit, Onassis Cardiac Surgery Center, No. 356 L. Syggrou, Athens 17674, Greece. stdimop@gmail.com |
| Key Words |
Chronic heart failure; Endothelial progenitor cells; Circulating endothelial cells; Maximal exercise; Cardiopulmonary exercise testing; Severity |
| Core Tip |
Vascular endothelial dysfunction is an underlying pathophysiological feature of chronic heart failure (CHF). Exercise has been proven to increase the mobilization of endothelial progenitor cells (EPCs), involved in vascular endothelial restoration and neo-vascularization, in healthy people and patients with co-morbidities. However, the effect of exercise on EPCs in patients with CHF of different severity remains unknown. In the present study, we compared the mobilization of EPCs in CHF patients of different severity, according to functional markers, after a symptom-limited cardiopulmonary exercise testing. No differences were found between severity groups, indicating thus the beneficial effect of exercise in these patients. |
| Publish Date |
2020-11-26 08:54 |
| Citation |
Kourek C, Karatzanos E, Psarra K, Georgiopoulos G, Delis D, Linardatou V, Gavrielatos G, Papadopoulos C, Nanas S, Dimopoulos S. Endothelial progenitor cells mobilization after maximal exercise according to heart failure severity. World J Cardiol 2020; 12:(11): 526-539 |
| URL |
https://www.wjgnet.com/1949-8462/full/v12/i11/526.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v12.i11.526 |
