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Articles Published Processes
11/20/2020 4:04:17 AM | Browse: 726 | Download: 1599
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Received |
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2020-06-19 13:49 |
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Peer-Review Started |
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2020-06-19 13:50 |
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To Make the First Decision |
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Return for Revision |
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2020-09-12 18:44 |
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Revised |
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2020-09-29 18:35 |
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Second Decision |
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2020-10-15 09:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-20 04:23 |
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Articles in Press |
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2020-10-20 04:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-24 02:55 |
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Typeset the Manuscript |
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2020-11-16 01:18 |
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Publish the Manuscript Online |
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2020-11-20 04:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Role of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xue-Ling Kang, Li-Rui He, Yao-Li Chen and Shu-Bin Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Sanming Project of Shenzhen |
SZSM201612041 |
| Shenzhen Science and Technology Innovation Commission Project |
GJHZ20180420180754917 and ZDSYS20190902092855097 |
| Postdoctoral Science Foundation of China |
2018M633095 |
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| Corresponding Author |
Shu-Bin Wang, MD, PhD, Chief Doctor, Department of Oncology, Peking University Shenzhen Hospital, Shenzhen Key Laboratory of Gastrointestinal Cancer Translational Research, China Cancer Institute of Shenzhen-Peking University-Hong Kong University of Science and Technology Medical Center, No. 1120 Lianhua Road, Futian District, Shenzhen 518036, Guangdong Province, China. shubinwang2013@163.com |
| Key Words |
Colorectal cancer; Cancer stem cells; Doublecortin-like kinase 1; Leucine-rich repeat-containing G-protein-coupled receptor 5; Cancer prognosis; Cancer progression |
| Core Tip |
The role of doublecortin-like kinase 1 (DCLK1) and leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) in patients with stage II/III colorectal cancer are uncertain. In this study, we found a positive correlation between the expression of DCLK1 and Lgr5, suggesting that DCLK1 and Lgr5 are involved in the malignant pathological development of colorectal cancer (CRC). High DCLK1 expression could predict the risk of recurrence and survival in CRC patients after surgery, which may be used as a potential cancer stem cells marker for the recurrence and survival of stage II/III CRC patients. |
| Publish Date |
2020-11-20 04:04 |
| Citation |
Kang XL, He LR, Chen YL, Wang SB. Role of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis. World J Gastroenterol 2020; 26(43): 6853-6866 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i43/6853.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i43.6853 |
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