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Articles Published Processes
1/1/2021 12:36:05 PM | Browse: 709 | Download: 1535
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Received |
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2020-06-24 14:41 |
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Peer-Review Started |
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2020-06-24 14:41 |
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To Make the First Decision |
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Return for Revision |
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2020-10-18 18:21 |
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Revised |
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2020-10-22 12:27 |
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Second Decision |
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2020-11-09 09:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-11-12 20:32 |
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Articles in Press |
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2020-11-12 20:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-17 02:57 |
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Typeset the Manuscript |
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2020-12-28 06:58 |
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Publish the Manuscript Online |
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2021-01-01 12:36 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Myeloid neoplasm with eosinophilia and rearrangement of platelet-derived growth factor receptor beta gene in children: Two case reports
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shi-Chong Wang and Wen-Yu Yang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wen-Yu Yang, PhD, Chief Doctor, Doctor, Doctor, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 288 Nanjing Road, Tianjin 300020, China. yangwenyu@ihcams.ac.cn |
| Key Words |
Myeloid neoplasm; Platelet-derived growth factor receptor beta rearrangement; Eosinophilia; Children; Imatinib; Case report |
| Core Tip |
In the present report, we described two pediatric patients diagnosed as myeloid neoplasm (MN) with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) rearrangement and reviewed relative literature to analyze the clinical and therapeutic features about this rare clinical entity. Although MN with PDGFRB rearrangement rarely occurs in children, we should alarm the clock for the possibility of this disease, and the mutant gene detect by fluorescence in situ hybridization are necessary once the disease is suspected. Imatinib had a considerable effect on children, though the dose of imatinib is still unclear. Moreover, we should pay more attention to the prognosis, life expectancy, side effects and life quality of these pediatric patients. |
| Publish Date |
2021-01-01 12:36 |
| Citation |
Wang SC, Yang WY. Myeloid neoplasm with eosinophilia and rearrangement of platelet-derived growth factor receptor beta gene in children: Two case reports. World J Clin Cases 2021; 9(1): 204-210 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i1/204.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i1.204 |
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