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1/15/2021 11:46:51 AM | Browse: 399 | Download: 729
Publication Name World Journal of Biological Chemistry
Manuscript ID 57814
Country/Territory United States
Received
2020-06-24 17:43
Peer-Review Started
2020-06-24 17:44
To Make the First Decision
Return for Revision
2020-11-04 17:43
Revised
2020-11-17 21:02
Second Decision
2020-12-30 08:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-12-30 15:30
Articles in Press
2020-12-30 15:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-01-15 03:03
Publish the Manuscript Online
2021-01-15 11:46
ISSN 1949-8454 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Basic Study
Article Title Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes
Manuscript Source Unsolicited Manuscript
All Author List Darcy R Denner, Maria LD Udan-Johns and Michael R Nichols
ORCID
Author(s) ORCID Number
Darcy R Denner http://orcid.org/0000-0003-1912-5957
Maria LD Udan-Johns http://orcid.org/0000-0003-0032-8703
Michael R Nichols http://orcid.org/0000-0001-5458-218X
Funding Agency and Grant Number
Corresponding Author Michael R Nichols, PhD, Professor, Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Blvd, St Louis, MO 63121, United States. nicholsmic@umsl.edu
Key Words Matrix metalloproteinase-9; Inflammation; Human monocytes; Tumor necrosis factor alpha; Cyclic adenosine monophosphate; Dimethyl sulfoxide
Core Tip This article describes the stimulation of matrix metalloproteinase-9 (MMP-9) and tumor necrosis factor α (TNFα) secretion from human monocyte cells by lipopolysaccharide, and the inhibition of this process by dimethyl sulfoxide and increased intracellular levels of 3',5'-cyclic adenosine monophosphate. The experimental findings demonstrated that dimethyl sulfoxide concentration must be carefully controlled in inflammatory studies, that MMP-9 secretion occurred downstream from TNFα secretion and that the two processes were distinct, and that TNFα is an integral component of the pathway leading to MMP-9 secretion.
Publish Date 2021-01-15 11:46
Citation Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14
URL https://www.wjgnet.com/1949-8454/full/v12/i1/1.htm
DOI https://dx.doi.org/10.4331/wjbc.v12.i1.1
Full Article (PDF) WJBC-12-1.pdf
Full Article (Word) WJBC-12-1.docx
Manuscript File 57814_Auto_Edited.docx
Answering Reviewers 57814-Answering reviewers.pdf
Audio Core Tip 57814-Audio core tip.m4a
Biostatistics Review Certificate 57814-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57814-Conflict-of-interest statement.pdf
Copyright License Agreement 57814-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57814-Grant application form(s).pdf
Peer-review Report 57814-Peer-review(s).pdf
Scientific Misconduct Check 57814-Bing-Yan JP-1.png
Scientific Misconduct Check 57814-Scientific misconduct check.pdf
Scientific Editor Work List 57814-Scientific editor work list.pdf