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12/19/2020 4:08:52 PM | Browse: 394 | Download: 508
Publication Name World Journal of Clinical Cases
Manuscript ID 57873
Country/Territory China
Received
2020-08-18 08:16
Peer-Review Started
2020-08-18 08:16
To Make the First Decision
Return for Revision
2020-09-13 04:55
Revised
2020-10-02 16:09
Second Decision
2020-10-23 11:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-10-26 04:35
Articles in Press
2020-10-26 04:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-11-13 04:05
Typeset the Manuscript
2020-12-08 05:40
Publish the Manuscript Online
2020-12-19 16:08
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Case Report
Article Title Eighty-year-old man with rare chronic neutrophilic leukemia caused by CSF3R T618I mutation: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Ya-Ping Li, Na Chen, Xian-Mei Ye and Yong-Shou Xia
ORCID
Author(s) ORCID Number
Ya-Ping Li http://orcid.org/0000-0002-1244-8677
Na Chen http://orcid.org/0000-0002-1244-8678
Xian-Mei Ye http://orcid.org/0000-0002-1244-8778
Yong-Shou Xia http://orcid.org/0000-0002-1244-8676
Funding Agency and Grant Number
Corresponding Author Yong-Shou Xia, MBBS, Associate Chief Physician, Department of Hematology, Chang'an Hospital, No. 17 Wenjing Road, Weiyang District, Xi'an 710000, Shaanxi Province, China. xiayshca@163.com
Key Words Chronic neutrophilic leukemia; Leukemia; Hyperplasia of interstitial neutrophil system; CSF3R; Case report; Hydroxyurea
Core Tip An 80-year-old man had a long history of interstitial pneumonia. His leukocyte levels were extremely high, while the fibrinogen and prothrombin activities were low. His urea, uric acid, and creatinine values are high, and there are reticulated fibers around the blood vessels, and the bone marrow fibrosis is obvious. His granulocyte system was extremely hyperplastic. Importantly, our gene mutation test found that the CSF3R gene was mutated. Therefore, we eventually diagnosed his symptoms as chronic neutrophilic leukemia (CNL). The particularity of the case lies in that CNL is often accompanied by splenomegaly, but the patient had no splenomegaly.
Publish Date 2020-12-19 16:08
Citation Li YP, Chen N, Ye XM, Xia YS. Eighty-year-old man with rare chronic neutrophilic leukemia caused by CSF3R T618I mutation: A case report and review of literature. World J Clin Cases 2020; 8(24): 6337-6345
URL https://www.wjgnet.com/2307-8960/full/v8/i24/6337.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i24.6337
Full Article (PDF) WJCC-8-6337.pdf
Full Article (Word) WJCC-8-6337.docx
Manuscript File 57873_Auto_Edited_WangTQ.docx
Answering Reviewers 57873-Answering reviewers.pdf
Audio Core Tip 57873-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 57873-Conflict-of-interest statement.pdf
Copyright License Agreement 57873-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 57873-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 57873-Language certificate.pdf
Peer-review Report 57873-Peer-review(s).pdf
Scientific Misconduct Check 57873-Bing-Wang JL-1.jpg
Scientific Misconduct Check 57873-Scientific misconduct check.pdf
Scientific Editor Work List 57873-Scientific editor work list.pdf