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8/26/2014 2:46:00 PM | Browse: 1044 | Download: 854
Publication Name World Journal of Gastroenterology
Manuscript ID 5789
Country/Territory Switzerland
Received
2013-09-25 12:48
Peer-Review Started
2013-09-25 16:56
To Make the First Decision
2013-12-26 10:56
Return for Revision
2014-01-17 10:19
Revised
Second Decision
2014-04-23 08:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-23 10:01
Articles in Press
2014-05-23 11:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-05-01 16:31
Typeset the Manuscript
2014-06-08 12:54
Publish the Manuscript Online
2014-06-21 13:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Recurrent Clostridium difficile infections: The importance of the intestinal microbiota
Manuscript Source Invited Manuscript
All Author List Marie Céline Zanella Terrier, Martine Louis Simonet, Philippe Bichard and Jean Louis Frossard
Funding Agency and Grant Number
Corresponding Author Jean Louis Frossard, MD, Service of Gastroenterology and Hepatology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva, Switzerland. jean-louis.frossard@hcuge.ch
Key Words Clostridium difficile infection; Clostridium difficile recurrence; fecal microbiota transplantation; ; stool transplantation; microbiota
Core Tip Despite current antibiotic treatments, Clostridium difficile infection (CDI) is a growing epidemic with increasing rates of recurrence, severity and mortality. The treatment of recurrent CDI thus represents a real challenge. This article simultaneously focuses on current guidelines for CDI treatment, the role of gut microbiota in CDI recurrence and current evidence about fecal microbiota transplantation (FMT) efficacy, adverse effects and acceptability. According to studies published to date, FMT use for recurrent CDI is associated with high resolution rates compared with standard antibiotic treatment. Further studies are needed to confirm FMT effectiveness, and to determine the long-term consequences and good administration practices.
Publish Date 2014-06-21 13:56
Citation Zanella Terrier MC, Simonet ML, Bichard P, Frossard JL. Recurrent Clostridium difficile infections: The importance of the intestinal microbiota. World J Gastroenterol 2014; 20(23): 7416-7423
URL http://www.wjgnet.com/1007-9327/full/v20/i23/7416.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i23.7416
Full Article (PDF) WJG-20-7416.pdf
Full Article (Word) WJG-20-7416.doc
Manuscript File 5789-Review.doc
Answering Reviewers 5789-Answering reviewers.pdf
Copyright License Agreement 5789-Copyright assignment.pdf
Peer-review Report 5789-Peer reviews.pdf
Scientific Editor Work List 5789-Scientific editor work list.doc