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Articles Published Processes
1/21/2021 3:12:07 AM | Browse: 754 | Download: 2043
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Received |
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2020-07-21 10:43 |
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Peer-Review Started |
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2020-07-20 03:33 |
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First Decision by Editorial Office Director |
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2020-10-21 20:14 |
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Return for Revision |
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2020-10-21 20:14 |
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Revised |
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2020-11-04 16:26 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2020-11-12 09:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-11-12 17:33 |
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Articles in Press |
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2020-11-12 17:33 |
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Edit the Manuscript by Language Editor |
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2020-11-26 03:11 |
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Typeset the Manuscript |
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2021-01-18 06:24 |
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Publish the Manuscript Online |
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2021-01-21 03:12 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Basic Study |
| Article Title |
Stem cell transplantation and/or adenoviral glial cell line-derived neurotrophic factor promoted functional recovery in hemiparkinsonian rats
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| Manuscript Source |
Invited Manuscript |
| All Author List |
May-Jywan Tsai, Shih-Chieh Hung, Ching-Feng Weng, Su-Fen Fan, Dann-Ying Liou, Wen-Cheng Huang, Kang-Du Liu and Henrich Cheng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Taipei Veterans General Hospital in Taiwan |
V106C-012, V107C-087 and V109C-018 |
| Ministry of Science and Technology in Taiwan |
MOST106-2314-B-075-023 |
| Ministry of Science and Technology in Taiwan |
MOST107-2314-B-010-023 |
| Ministry of Science and Technology in Taiwan |
MOST107-2314-B-075-021 |
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| Corresponding Author |
Henrich Cheng, MD, PhD, Full Professor, Surgeon, Department of Neurosurgery, Taipei Veterans General Hospital, Center for Neural Regeneration, Neurological Institute, No. 322 Section 2, Shih-Pai Road, Beitou District, Taipei 112, Taiwan. hc_cheng@vghtpe.gov.tw |
| Key Words |
Stem cells; Transplantation; Parkinson’s disease; Glial cell line-derived neurotrophic factor; Adenovirus; Neuroregeneration |
| Core Tip |
Strategies to stop neurodegeneration in Parkinson’s disease are currently unavailable. In the present study, transplantation of neurally induced mesenchymal stem cells or overexpressing glial cell line-derived neurotrophic factor to the substantia nigra of hemiparkinsonian rats not only exerted a regenerative effect, but promoted functional restoration. This treatment may have the potential to improve clinical outcome. |
| Publish Date |
2021-01-21 03:12 |
| Citation |
Tsai MJ, Hung SC, Weng CF, Fan SF, Liou DY, Huang WC, Liu KD, Cheng H. Stem cell transplantation and/or adenoviral glial cell line-derived neurotrophic factor promoted functional recovery in hemiparkinsonian rats. World J Stem Cells 2021; 13(1): 78-90 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i1/78.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i1.78 |
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