Publication Name	World Journal of Gastroenterology
Manuscript ID	5806
Country	China

Received	2013-09-27 06:20
Peer-Review Started	2013-09-28 11:03
To Make the First Decision	2013-10-14 21:10
Return for Revision	2013-10-16 15:58
Revised	2013-10-22 19:58
Second Decision	2013-11-04 18:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-05 11:19
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-11-13 18:17
Typeset the Manuscript	2013-11-21 10:29
Publish the Manuscript Online	2013-12-11 16:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Scotomas in molecular virology and epidemiology of hepatitis C virus
Manuscript Source	Invited Manuscript
All Author List	Yue Wang
Funding Agency and Grant Number
Corresponding Author	Yue Wang, Professor, National Institute for Viral Disease Control and Prevention, China CDC, Xicheng District, Yingxin Rd, Beijing 100052, China. euy-tokyo@umin.ac.jp
Key Words	Hepatitis C virus; Hepatitis C virus lifecycle; Molecular virology; Hepatitis C virus models; Epidemiology
Core Tip	The review summarizes the advancements, as well as remaining scotomas, in the molecular virology of hepatitis C virus (HCV). We emphasize the contributions of HuH-7 hepatocellular carcinoma cell line to development of the HCV replicon, cell culture-derived HCV, and HCV pseudoparticles. In addition, we reiterate the importance of epidemiological issues because accurate assessment of HCV-related disease burden has been overlooked. This review provides a history of the fight against HCV, which has required scientists to avail themselves to the best of modern biomedical technology, which in turn has enriched our knowledge of virology and cellular physiology.
Publish Date	2013-12-11 16:13
Citation	Wang Y. Scotomas in molecular virology and epidemiology of hepatitis C virus. World J Gastroenterol 2013; 19(44): 7910-7921
URL	http://www.wjgnet.com/1007-9327/full/v19/i44/7910.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i44.7910

Full Article (PDF)	WJG-19-7910.pdf
Manuscript File	5806-Review.doc
Answering Reviewers	5806-Answering reviewers.pdf
Copyright License Agreement	5806-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5806-Language certificate.pdf
Peer-review Report	5806-Peer reviews.pdf
Scientific Editor Work List	5806-Scientific editor work list.doc