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9/1/2014 2:51:00 PM | Browse: 964 | Download: 1026
Publication Name World Journal of Gastroenterology
Manuscript ID 5808
Country/Territory Taiwan
Received
2013-09-27 06:25
Peer-Review Started
2013-09-28 09:48
To Make the First Decision
2013-10-22 16:38
Return for Revision
2013-10-23 10:38
Revised
2013-11-10 21:08
Second Decision
2013-12-13 14:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-13 14:51
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-01-09 18:03
Publish the Manuscript Online
2014-03-18 14:14
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Topic Highlights
Article Title Useful biomarkers for assessment of hepatitis C virus infection-associated autoimmune disorders
Manuscript Source Invited Manuscript
All Author List Deng-Ho Yang, Ling-Jun Ho and Jenn-Haung Lai
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Council (In part) 101-2314-B-182A-103-MY3
Chang Gung Memorial Hospital CMRPG3B1751E
Corresponding Author Jenn-Haung Lai, MD, PhD, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, No.5, Fusing St., Gueishan Township, Taoyuan 333, Taiwan. laiandho@gmail.com
Key Words Hepatitis C virus; Autoantibody; Autoimmune; Biomarker; Cytokine
Core Tip Patients with hepatitis C virus (HCV) infection may develop a variety of immunological manifestations simulating those observed in patients with autoimmune disorders. Concurrently, many laboratory abnormalities commonly present in autoimmune disorders may be detected. Overactivation and proliferation of B lymphocytes, via the interaction with the surface protein of HCV, contributes in part to these abnormalities. These clinical and laboratory findings can potentially mid-lead to the diagnosis of primary autoimmune disorders and result in inappropriate therapy. This review addresses the importance of several clinical and laboratory biomarkers and their usefulness in distinguishing HCV infection-related from primary autoimmune disorder-related etiologies.
Publish Date 2014-03-18 14:14
Citation Yang DH, Ho LJ, Lai JH. Useful biomarkers for assessment of hepatitis C virus infection-associated autoimmune disorders. World J Gastroenterol 2014; 20(11): 2962-2970
URL http://www.wjgnet.com/1007-9327/full/v20/i11/2962.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i11.2962
Full Article (PDF) WJG-20-2962.pdf
Full Article (Word) WJG-20-2962.doc
Manuscript File 5808-Review.doc
Answering Reviewers 5808-Answering reviewers.pdf
Copyright License Agreement 5808-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 5808-Language certificate.pdf
Peer-review Report 5808-Peer reviews.pdf
Scientific Editor Work List 5808-Scientific editor work list.doc