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Articles Published Processes
9/1/2014 2:51:00 PM | Browse: 1076 | Download: 1276
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Received |
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2013-09-27 06:25 |
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Peer-Review Started |
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2013-09-28 09:48 |
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To Make the First Decision |
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2013-10-22 16:38 |
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Return for Revision |
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2013-10-23 10:38 |
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Revised |
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2013-11-10 21:08 |
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Second Decision |
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2013-12-13 14:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-12-13 14:51 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-09 18:03 |
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Publish the Manuscript Online |
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2014-03-18 14:14 |
Category |
Immunology |
Manuscript Type |
Topic Highlights |
Article Title |
Useful biomarkers for assessment of hepatitis C virus infection-associated autoimmune disorders
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Manuscript Source |
Invited Manuscript |
All Author List |
Deng-Ho Yang, Ling-Jun Ho and Jenn-Haung Lai |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Science Council (In part) |
101-2314-B-182A-103-MY3 |
Chang Gung Memorial Hospital |
CMRPG3B1751E |
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Corresponding Author |
Jenn-Haung Lai, MD, PhD, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, No.5, Fusing St., Gueishan Township, Taoyuan 333, Taiwan. laiandho@gmail.com |
Key Words |
Hepatitis C virus; Autoantibody; Autoimmune; Biomarker; Cytokine |
Core Tip |
Patients with hepatitis C virus (HCV) infection may develop a variety of immunological manifestations simulating those observed in patients with autoimmune disorders. Concurrently, many laboratory abnormalities commonly present in autoimmune disorders may be detected. Overactivation and proliferation of B lymphocytes, via the interaction with the surface protein of HCV, contributes in part to these abnormalities. These clinical and laboratory findings can potentially mid-lead to the diagnosis of primary autoimmune disorders and result in inappropriate therapy. This review addresses the importance of several clinical and laboratory biomarkers and their usefulness in distinguishing HCV infection-related from primary autoimmune disorder-related etiologies. |
Publish Date |
2014-03-18 14:14 |
Citation |
Yang DH, Ho LJ, Lai JH. Useful biomarkers for assessment of hepatitis C virus infection-associated autoimmune disorders. World J Gastroenterol 2014; 20(11): 2962-2970 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i11/2962.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i11.2962 |
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