Publication Name	World Journal of Gastroenterology
Manuscript ID	5809
Country	Japan

Received	2013-09-27 06:28
Peer-Review Started	2013-09-28 09:38
To Make the First Decision	2013-10-14 21:10
Return for Revision	2013-10-16 16:04
Revised	2013-10-22 21:07
Second Decision	2013-11-04 18:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-05 11:20
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-11-19 05:08
Typeset the Manuscript	2013-11-26 21:25
Publish the Manuscript Online	2013-12-18 10:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Helicobacter pylori and gastric mucosa-associated lymphoid tissue lymphoma: Recent progress in pathogenesis and management
Manuscript Source	Invited Manuscript
All Author List	Shotaro Nakamura and Takayuki Matsumoto
Funding Agency and Grant Number
Corresponding Author	Shotaro Nakamura, MD, PhD, Department of R/D for Surgical Support System, Center for Advanced Medical Innovation, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. shonaka@intmed2.med.kyushu-u.ac.jp
Key Words	Gastric lymphoma; Mucosa-associated lymphoid tissue lymphoma; Helicobacter pylori; Nuclear factor κB
Core Tip	Recent progress in the research regarding the molecular pathogenesis and management of gastric mucosa-associated lymphoid tissue (MALT) lymphoma is reviewed. Helicobacter pylori (H. pylori) eradication leads to complete disease remission in 50%-90% of cases. In H. pylori-independent cases, activation of nuclear factor ?B pathway by chromosomal translocations such as t(11;18)/API2-MALT1, or inactivation of A20 are considered to contribute to the lymphomagenesis. A recent Japanese multicenter study confirmed the excellent long-term outcome of gastric MALT lymphoma after H. pylori eradication. Strategies for patients not responding to H. pylori eradication should be tailored in consideration of clinical stage and the disease extent in each patient.
Publish Date	2013-12-18 10:39
Citation	Nakamura S, Matsumoto T. Helicobacter pylori and gastric mucosa-associated lymphoid tissue lymphoma: Recent progress in pathogenesis and management. World J Gastroenterol 2013; 19(45): 8181-8187
URL	http://www.wjgnet.com/1007-9327/full/v19/i45/8181.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i45.8181

Full Article (PDF)	WJG-19-8181.pdf
Manuscript File	5809-Review.doc
Answering Reviewers	5809-Answering reviewers.pdf
Copyright License Agreement	5809-Copyright assignment.pdf
Peer-review Report	5809-Peer reviews.pdf
Scientific Editor Work List	5809-Scientific editor work list.doc