Publication Name	World Journal of Gastroenterology
Manuscript ID	5813
Country	United States

Received	2013-09-27 06:39
Peer-Review Started	2013-09-28 09:29
To Make the First Decision	2013-10-22 16:37
Return for Revision	2013-10-28 09:01
Revised	2013-10-28 18:58
Second Decision	2014-01-15 20:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-15 20:37
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-04-23 16:43
Publish the Manuscript Online	2014-05-14 10:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	History of Helicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer
Manuscript Source	Invited Manuscript
All Author List	David Y Graham
Funding Agency and Grant Number
Corresponding Author	David Y Graham, MD, Michael E DeBakey VA Medical Center, Baylor College of Medicine, 2002 Holcombe Blvd., Rm 3A-318B (111D), Houston, TX 77030, United States. dgraham@bcm.edu
Key Words	Helicobacter pylori; Duodenal ulcer; Gastric ulcer; Gastric cancer; Medical history; Ulcer surgery; Epidemiology; Gastritis; Atrophic gastritis; Antiquity
Core Tip	Helicobacter pylori (H. pylori)-related diseases reflect the pattern and extent of gastritis/atrophy (i.e., duodenal ulcer signifies the presence of non-atrophic gastritis whereas gastric ulcer and gastric cancer signify atrophic gastritis). While, it has been suggested that gastric ulcer and duodenal ulcer both arose or became more frequent in Europe in the 19th century, the available data are more consistent with a change in the pattern of gastritis related to environmental conditions which previously had resulted primarily in atrophic gastritis. Duodenal ulcer then dominated clinically until the rapid decline in H. pylori transmission resulted in a rapid decline in all H. pylori-related diseases.
Publish Date	2014-05-14 10:58
Citation	Graham DY. History of Helicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer. World J Gastroenterol 2014; 20(18): 5191-5204
URL	http://www.wjgnet.com/1007-9327/full/v20/i18/5191.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i18.5191

Full Article (PDF)	WJG-20-5191.pdf
Full Article (Word)	WJG-20-5191.doc
Manuscript File	5813-Review.doc
Answering Reviewers	5813-Answering reviewers.pdf
Copyright License Agreement	5813-Copyright assignment.pdf
Peer-review Report	5813-Peer reviews.pdf
Scientific Editor Work List	5813-Scientific editor work list.doc