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Articles Published Processes
1/7/2021 8:35:07 AM | Browse: 852 | Download: 2008
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Received |
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2020-08-21 08:57 |
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Peer-Review Started |
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2020-08-16 07:55 |
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First Decision by Editorial Office Director |
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2020-09-21 17:14 |
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Return for Revision |
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2020-09-21 17:14 |
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Revised |
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2020-10-05 14:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2020-10-26 14:56 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-10-26 18:04 |
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Articles in Press |
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2020-10-26 18:04 |
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Edit the Manuscript by Language Editor |
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2020-11-17 14:11 |
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Typeset the Manuscript |
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2021-01-06 07:06 |
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Publish the Manuscript Online |
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2021-01-07 08:35 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Metformin regulates inflammation and fibrosis in diabetic kidney disease through TNC/TLR4/NF-κB/miR-155-5p inflammatory loop
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Zhou, Xiao-Yu Ma, Jin-Yu Han, Min Yang, Chuan Lv, Ying Shao, Yi-Li Wang, Jia-Yi Kang and Qiu-Yue Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development Program of China |
2018YFC1313901 |
| The Higher School Highend Talent Team Construction of Liaoning Province |
[2014]187 |
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| Corresponding Author |
Qiu-Yue Wang, PhD, Professor, Department of Endocrinology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110000, Liaoning Province, China. wqycmu123@163.com |
| Key Words |
Tenascin-C; miR-155-5p; Metformin; Type 2 diabetes mellitus; Diabetic kidney disease; Toll-like receptor 4 |
| Core Tip |
Investigate the correlation between serum tenascin-C (TNC) levels and urine albumin clearance ratios in a total of 380 patients with type 2 diabetes mellitus, TNC can regulates mir-155-5p through Toll-like receptor 4/nuclear factor κB signaling in rat mesangial cells under hyperglycaemia condition, metformin can inhibit inflammation and fibrosis in diabetic kidney disease through TNC. |
| Publish Date |
2021-01-07 08:35 |
| Citation |
Zhou Y, Ma XY, Han JY, Yang M, Lv C, Shao Y, Wang YL, Kang JY, Wang QY. Metformin regulates inflammation and fibrosis in diabetic kidney disease through TNC/TLR4/NF-κB/miR-155-5p inflammatory loop. World J Diabetes 2021; 12(1): 19-46
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| URL |
https://www.wjgnet.com/1948-9358/full/v12/i1/19.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i1.19 |
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