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Articles Published Processes
12/13/2020 5:45:32 AM | Browse: 591 | Download: 886
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Received |
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2020-07-09 18:03 |
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Peer-Review Started |
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2020-07-09 18:04 |
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To Make the First Decision |
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Return for Revision |
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2020-10-06 16:40 |
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Revised |
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2020-10-20 03:46 |
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Second Decision |
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2020-11-11 09:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-11-12 17:02 |
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Articles in Press |
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2020-11-12 17:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-12-02 05:56 |
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Publish the Manuscript Online |
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2020-12-13 05:45 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Minireviews |
| Article Title |
SX-fraction: Promise for novel treatment of type 2 diabetes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sensuke Konno |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sensuke Konno, PhD, Associate Professor, Department of Urology, New York Medical College, BSB Room A03, Valhalla, NY 10595, United States. sensuke_konno@nymc.edu |
| Key Words |
SX-fraction; Diabetes; Anti-diabetic; Hypoglycemic; Insulin signal pathway; |
| Core Tip |
We have been searching for a natural agent capable of controlling diabetic conditions in patients with type 2 diabetes for years. We then came across “SX-fraction (SXF)”, isolated from maitake mushroom (Grifola frondorsa), with anti-diabetic and hypoglycemic activities. In this short review, we chronologically described several key studies of SXF such as animal studies using diabetic mice (to demonstrate anti-diabetic activity), limited clinical studies on volunteer patients with type 2 diabetes (to show hypoglycemic activity), and in vitro study using skeletal muscle cells (to elucidate the hypoglycemic mechanism). After all, SXF appears to be a natural, safe, effective agent for treatment of patients with type 2 diabetes, although more (clinical) studies are yet required for confirmation. |
| Publish Date |
2020-12-13 05:45 |
| Citation |
Konno S. SX-fraction: Promise for novel treatment of type 2 diabetes. World J Diabetes 2020; 11(12): 572-583 |
| URL |
https://www.wjgnet.com/1948-9358/full/v11/i12/572.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v11.i12.572 |
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