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Articles Published Processes
12/27/2020 5:30:53 AM | Browse: 605 | Download: 972
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Received |
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2020-07-10 14:45 |
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Peer-Review Started |
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2020-07-10 14:46 |
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To Make the First Decision |
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Return for Revision |
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2020-09-17 22:20 |
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Revised |
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2020-09-29 16:26 |
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Second Decision |
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2020-10-15 09:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-15 16:25 |
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Articles in Press |
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2020-10-15 16:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-02 22:55 |
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Typeset the Manuscript |
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2020-12-24 10:29 |
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Publish the Manuscript Online |
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2020-12-27 05:30 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Minibrain-related kinase/dual-specificity tyrosine-regulated kinase 1B implication in stem/cancer stem cells biology
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nikolaos Kokkorakis and Maria Gaitanou |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maria Gaitanou, BSc, PhD, Research Assistant Professor, Laboratory of Cellular and Molecular Neurobiology-Stem cells, Hellenic Pasteur Institute, Vas. Sofias 127, Athens 11521, Greece. mgaitanou@pasteur.gr |
| Key Words |
Dual-specificity tyrosine-regulated kinase 1B; Minibrain-related kinase; Stem cells; Cancer stem cells; Quiescence; Cell proliferation/differentiation |
| Core Tip |
Dual-specificity tyrosine phosphorylation-regulated kinase 1B (DYRK1B), also known as Minibrain-related kinase (MIRK) is the well-studied member of the DYRK kinases family. DYRK1B is a key regulator of signaling pathways that control proliferation and differentiation, and is critical for developmental processes and cell homeostasis. In this review, we aim to bring together what is known about the functional integration and cross-talk between DYRK1B and several pathways such as Sonic Hedgehog (HH), RAS and PI3K/mTOR/AKT pathways and how this might affect the behavior of stem cells in development and disease, taking into consideration potent therapeutic interventions and approaches. |
| Publish Date |
2020-12-27 05:30 |
| Citation |
Kokkorakis N, Gaitanou M. Minibrain-related kinase/dual-specificity tyrosine-regulated kinase 1B implication in stem/cancer stem cells biology. World J Stem Cells 2020; 12(12): 1553-1575 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i12/1553.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i12.1553 |
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