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Articles Published Processes
12/27/2020 5:30:53 AM | Browse: 644 | Download: 1526
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Received |
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2020-07-16 21:00 |
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Peer-Review Started |
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2020-07-16 21:01 |
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To Make the First Decision |
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Return for Revision |
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2020-08-09 14:38 |
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Revised |
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2020-10-09 18:03 |
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Second Decision |
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2020-11-03 09:17 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-11-05 18:32 |
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Articles in Press |
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2020-11-05 18:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-13 07:07 |
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Typeset the Manuscript |
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2020-12-24 10:52 |
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Publish the Manuscript Online |
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2020-12-27 05:30 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Influence of donor age on the differentiation and division capacity of human adipose-derived stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cintia DS Horinouchi, María Julia Barisón, Anny W Robert, Crisciele Kuligovski, Alessandra M Aguiar and Bruno Dallagiovanna |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico |
442353/2019-7 and 442375/2019-0 |
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| Corresponding Author |
Bruno Dallagiovanna, PhD, Research Scientist, Stem Cells Basic Biology Laboratory, Instituto Carlos Chagas, Rua Professor Algacyr Munhoz Mader, 3775, Curitiba 81350010, Paraná, Brazil. bruno.dallagiovanna@fiocruz.br |
| Key Words |
Adipose-derived stem cells; Stem cells; Adipogenesis; Osteogenesis; Cell differentiation; Donor age |
| Core Tip |
Adipose-derived stem cells are adult multipotent stem cells with great therapeutic potential for a variety of diseases. Donor’s intrinsic characteristics, such as sex, health conditions and age, have been claimed to be one of the main factors responsible for affecting the quality and the performance of these cells. Regarding donor age, the literature shows many conflicting observations. Here, we evaluated the proliferation and differentiation potential of adipose-derived stem cells isolated from lipoaspirates from elderly and young female donors. Our results demonstrated that age does not seem to significantly affect the cell division or adipogenic or osteogenic potential of these cells. |
| Publish Date |
2020-12-27 05:30 |
| Citation |
Horinouchi CDS, Barisón MJ, Robert AW, Kuligovski C, Aguiar AM, Dallagiovanna B. Influence of donor age on the differentiation and division capacity of human adipose-derived stem cells. World J Stem Cells 2020; 12(12): 1640-1651 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i12/1640.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i12.1640 |
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