Publication Name	World Journal of Gastroenterology
Manuscript ID	5836
Country	Italy

Received	2013-09-28 14:57
Peer-Review Started	2013-09-29 13:17
To Make the First Decision	2013-10-29 12:32
Return for Revision	2013-10-30 10:39
Revised	2013-11-06 22:37
Second Decision	2013-12-13 14:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-13 14:54
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-26 10:51
Publish the Manuscript Online	2014-03-12 14:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Review
Article Title	Hepatitis C virus, mitochondria and auto/mitophagy: Exploiting a host defense mechanism
Manuscript Source	Invited Manuscript
All Author List	Vitalba Ruggieri, Carmela Mazzoccoli, Valerio Pazienza, Angelo Andriulli, Nazzareno Capitanio and Claudia Piccoli
Funding Agency and Grant Number
Corresponding Author	Claudia Piccoli, PhD, Department of Medical and Experimental Medicine, University of Foggia, Via Napoli 25, 71122 Foggia, Italy. claudia.piccoli@unifg.it
Key Words	Hepatitis C virus; Mitochondrial dysfunctions; Immunity; Autophagy; Mitophagy
Core Tip	Among the strategies that host cells have evolved in the hard fight for their survival against viruses, auto/mitophagy processes have an emerging role. As preferential targets of hepatitis C virus (HCV) attack, mitochondria effectively establish themselves as an integral part of the host cell defense and mitophagy, as very recently unveiled, seriously impacts the course of hepatitis C infection. Aim of this review is to explore the current literature about the mechanisms that regulate the critical interplay between HCV and mitochondria, with particular regard to the strategies that the virus evolved to subvert and manipulate the auto/mitophagy pathways to its purposes.
Publish Date	2014-03-12 14:46
Citation	Ruggieri V, Mazzoccoli C, Pazienza V, Andriulli A, Capitanio N, Piccoli C. Hepatitis C virus, mitochondria and auto/mitophagy: Exploiting a host defense mechanism. World J Gastroenterol 2014; 20(10): 2624-2633
URL	http://www.wjgnet.com/1007-9327/full/v20/i10/2624.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i10.2624

Full Article (PDF)	WJG-20-2624.pdf
Full Article (Word)	WJG-20-2624.doc
Manuscript File	5836-Review.doc
Answering Reviewers	5836-Answering reviewers.pdf
Copyright License Agreement	5836-Copyright assignment.pdf
Peer-review Report	5836-Peer reviews.pdf
Scientific Editor Work List	5836-Scientific editor work list.doc