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9/1/2014 5:04:00 PM | Browse: 380 | Download: 211
Publication Name World Journal of Gastroenterology
Manuscript ID 5836
Country of Manuscript Source Italy
Received
2013-09-28 14:57
Peer-Review Started
2013-09-29 13:17
To Make the First Decision
2013-10-29 12:32
Return for Revision
2013-10-30 10:39
Revised
2013-11-06 22:37
Second Decision
2013-12-13 14:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-13 14:54
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-02-26 10:51
Publish the Manuscript Online
2014-03-12 14:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Biochemistry and Molecular Biology
Manuscript Type Review
Article Title Hepatitis C virus, mitochondria and auto/mitophagy: Exploiting a host defense mechanism
Manuscript Source Invited Manuscript
All Author List Vitalba Ruggieri, Carmela Mazzoccoli, Valerio Pazienza, Angelo Andriulli, Nazzareno Capitanio and Claudia Piccoli
Funding Agency and Grant Number
Corresponding author Claudia Piccoli, PhD, Department of Medical and Experimental Medicine, University of Foggia, Via Napoli 25, 71122 Foggia, Italy. claudia.piccoli@unifg.it
Keywords Hepatitis C virus; Mitochondrial dysfunctions; Immunity; Autophagy; Mitophagy
Core Tip Among the strategies that host cells have evolved in the hard fight for their survival against viruses, auto/mitophagy processes have an emerging role. As preferential targets of hepatitis C virus (HCV) attack, mitochondria effectively establish themselves as an integral part of the host cell defense and mitophagy, as very recently unveiled, seriously impacts the course of hepatitis C infection. Aim of this review is to explore the current literature about the mechanisms that regulate the critical interplay between HCV and mitochondria, with particular regard to the strategies that the virus evolved to subvert and manipulate the auto/mitophagy pathways to its purposes.
Publish Date 2014-03-12 14:46
Citation Ruggieri V, Mazzoccoli C, Pazienza V, Andriulli A, Capitanio N, Piccoli C. Hepatitis C virus, mitochondria and auto/mitophagy: Exploiting a host defense mechanism. World J Gastroenterol 2014; 20(10): 2624-2633
Url http://www.wjgnet.com/1007-9327/full/v20/i10/2624.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i10.2624
Full Article (PDF) WJG-20-2624.pdf
Full Article (Word) WJG-20-2624.doc
Manuscript File 5836-Review.doc
Answering Reviewers 5836-Answering reviewers.pdf
Copyright License Agreement 5836-Copyright assignment.pdf
Peer-review Report 5836-Peer reviews.pdf
Scientific Editor Work List 5836-Scientific editor work list.doc